The effect of ethanol extract of soursop leaf (Annona muricata L.) on Adhesion of Streptococcus mutans ATCC 35668 to hydroxyapatite discs

Rahman, Friska Ani; Haniastuti, Tetiana

doi:10.22146/majkedgiind.24852

Cited by 8 publications

(14 citation statements)

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“…triangularis adhesion to the plastic surface and contact lens. This result is in agreement with the previous study reported on A. muricata inhibited the adhesion of Streptococcus mutans on hydroxyapatite discs, resulting in plaque forming inhibition (Rahman et al,2018). It was also observed that flat and adjacent trophozoites adhered to the surface via several acanthopodia in the control, while the treated trophozoites demonstrated shrunken cells.…”

Section: Discussionsupporting

confidence: 93%

Potential anti-Acanthamoeba and anti-adhesion activities of Annona muricata and Combretum trifoliatum extracts and their synergistic effects in combination with chlorhexidine against Acanthamoeba triangularis trophozoites and cysts

Mitsuwan

Sin

Keo³

et al. 2021

Heliyon

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Plants with medicinal properties have been used in the treatment of several infectious diseases, including Acanthamoeba infections. The medicinal properties of Cambodian plant extracts; Annona muricata and Combretum trifoliatum were investigated against Acanthamoeba triangularis. A total of 39 plant extracts were evaluated and, as a result, 22 extracts showed positive anti-Acanthamoeba activity. Of the 22 extracts, 9 and 4 extracts showed anti-Acanthamoeba activity against trophozoites and cysts of A. triangularis, respectively. The minimum inhibitory concentration of A. muricata and C. trifoliatum extracts against trophozoites and cysts was 500 and 1,000 μg/mL, respectively. The combination of A. muricata at 1/4ÂMIC with chlorhexidine at 1/8ÂMIC demonstrated a synergistic effect against trophozoites, but partial synergy against cysts. A 40% reduction in trophozoites and 60% of cysts adhered to the plastic surface treated with both extracts at 1/2ÂMIC were noted comparing to the control (P < 0.05). Furthermore, a reduction of 80% and 90% of trophozoites adhered to the surface was observed after pretreatment with A. muricata and C. trifoliatum extracts, respectively. A 90% of cysts adhered to the surface was decreased with pre-treatment of A. muricata at 1/2ÂMIC (P < 0.05). A 75% of trophozoites and cysts from Acanthamoeba adhered to the surface were removed after treatment with both extracts at 4ÂMIC (P < 0.05). In the model of contact lens, 1 log cells/mL of trophozoites and cysts was significantly decreased post-treatment with both extracts compared to the control. Trophozoites showed strong loss of acanthopodia and thorn-like projection pseudopodia, while cysts demonstrated retraction and folded appearance treated with both extracts when observed by SEM, which suggests the potential benefits of the medicinal plants A. muricata and C. trifoliatum as an option treatment against Acanthamoeba infections.

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Section: Discussionsupporting

confidence: 93%

Potential anti-Acanthamoeba and anti-adhesion activities of Annona muricata and Combretum trifoliatum extracts and their synergistic effects in combination with chlorhexidine against Acanthamoeba triangularis trophozoites and cysts

Mitsuwan

Sin

Keo³

et al. 2021

Heliyon

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“…Alkaloids are also able to disrupt the integrity of peptidoglycan components in bacterial cells. Peptidoglycan is a component of cell wall in bacteria that any disruption in peptidoglycan will inhibit wall layer formation and could lead to cell death (Rahman et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

The Toxicity and Antibacterial Properties of Calamus ornatus Bl. Rattan Fruit

et al. 2019

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Calamus ornatus Bl., locally known as rotan mantang or rotan seuti is one of the commercial rattan species growing in the forests of East Borneo. Its fruit is edible, like the fruits of other species of rattan, and it has been used by the local people as traditional medicine to treat stomachache or toothache. Until recently, there has not been any study investigating the benefits of the fruit for medicinal or other purposes. This research aimed to discover the bio-activity potentials of Calamus ornatus Bl. fruits by identifying its toxicity level and antibacterial potentials. The parts of the fruit (pericarp, flesh, and seed) were extracted using ethanol as solvent to extract samples. The toxicity was analyzed by using the Brine Shrimp Lethality Test (BSLT) method while the antibacterial activity was tested using a well diffusion method. Low toxicity was found in the flesh, whereas the pericarp and the seed were non-toxic. Antibacterial activity against Escherichia coli was found in the pericarp and the seed, while antibacterial activity against Streptococcus mutans was found in the pericarp and the flesh.

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“…Besides that, alkaloids can also interfere with the integrity of the peptidoglycan component in bacterial cells. Peptidoglycan is a component of the building of bacterial cell walls so that interference will cause the cell wall layer not to form intact and cause cell death [17].…”

Section: Antibacterialmentioning

confidence: 99%

“…The antibacterial mechanism possessed by tannins is its ability to inhibit the synthesis of chitin used to form cell walls in fungi and damage the cell membrane so that fungal growth is inhibited. Tannins are also lipophilic compounds that are easily attached to the cell wall and cause damage to the cell wall [17].…”

Section: Antibacterialmentioning

confidence: 99%

Increased Benefits of Calamus manan Miq. Fruit by Its Potential Bioactivity

Salusu¹,

Ariani²,

Budiarso³

et al. 2021

Advances in Biological Sciences Research

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Rattan manau (Calamus manan Miq.) is one of some commercial rattan species that grow in East Kalimantan forests. Its fruit is edible, similarly to some other species' fruits, and the local community traditionally uses it as medicine for stomach and toothache. There has not been any research related to investigating its fruit's benefits for medical purposes or others. This study aims to determine the potential of bioactivity in Calamus manan Miq's fruit, including some of its properties, such as phytochemical content, antioxidant, toxicity, and antibacterial activity. Parts of fruit, pericarp, flesh and seed were examined by using ethanol as a solvent. The study results show that the pericarp and seed have higher antioxidant activity than fruit flesh where the seed has an IC50 value of 25,04 ppm, the pericarp of 41,17 ppm and fruit flesh of 170,19 ppm. The examination result of toxicity properties using the BSLT (Brine Shrimp Lethality Test) test shows the fruit of rattan manau is not toxic. Examination on antibacterial activity for two types of bacteria showed that pericarp and seeds have antibacterial activity against Escherichia coli, rated as an intense level. In contrast, for Streptococcus mutans it is rated as a weak category.

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The effect of ethanol extract of soursop leaf (Annona muricata L.) on Adhesion of Streptococcus mutans ATCC 35668 to hydroxyapatite discs

Cited by 8 publications

References 0 publications

Potential anti-Acanthamoeba and anti-adhesion activities of Annona muricata and Combretum trifoliatum extracts and their synergistic effects in combination with chlorhexidine against Acanthamoeba triangularis trophozoites and cysts

Potential anti-Acanthamoeba and anti-adhesion activities of Annona muricata and Combretum trifoliatum extracts and their synergistic effects in combination with chlorhexidine against Acanthamoeba triangularis trophozoites and cysts

The Toxicity and Antibacterial Properties of Calamus ornatus Bl. Rattan Fruit

Increased Benefits of Calamus manan Miq. Fruit by Its Potential Bioactivity

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