The Effect of Feeding Various Levels of Calcium and Phosphorus on the Performance and Absorption of Chlortetracyline of Caged Layers

Eoff, H. J.; Davies, Robert P.; Ferguson, T. M.; Couch, J. R.

doi:10.3382/ps.0411071

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…This tendency was noted each time that this change of diets was made, and it was evident in both egg production and strength of shell. This observation is in contrast to that noted by Eoff et al (1962), previously cited, in which production of their depleted chickens (fed diets containing 1.35 percent and 0.45 percent of calcium) lagged slightly below the controls after the highest level of calcium (2.37 percent) was restored in the diet.…”

Section: Resultscontrasting

confidence: 85%

“…The latter group also noted marked reductions in strength and thickness of the egg shells within the five-day period, in one of two experiments. Eoff et al (1962) reduced the level of calcium in the diet of pullets from 2.37 percent to 1.35 percent for 28 days, and in the diet of some others from 2.37 percent to 0.45 percent for nine days. Significant reductions in egg production were noted in both instances.…”

Section: Discussionmentioning

confidence: 97%

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The Effects of Low Levels of Calcium in the Diet of Laying Chickens

Mehring

Titus

1964

Poultry Science

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Section: Resultscontrasting

confidence: 85%

Section: Discussionmentioning

confidence: 97%

The Effects of Low Levels of Calcium in the Diet of Laying Chickens

Mehring

Titus

1964

Poultry Science

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“…Thus, the levels noted in the serum probably approach the highest level in the blood each day. Since the antibiotic is eliminated rapidly from blood serum following withdrawal of the antibiotic, as shown by the results of Brown and Bachmann (1959), Pensack et al (1960) and Eoff et al (1962c) as well as the results of the previous experiment, it is likely that blood serum CTC levels vary considerably during the day when a "breakfast program" is followed. It would be interesting to know whether attaining a high blood level of CTC each day, followed by a decline, is as efficacious in treatment of disease as more steadily maintaining a lower level of the drug.…”

Section: Resultsmentioning

confidence: 85%

“…Even when antibiotic is fed throughout the day, blood serum CTC levels probably vary over a wide range. Eoff et al (1962c) reported that two-thirds of the antibiotic disappeared 9 hours after the antibiotic was withdrawn from the diet. The blood levels achieved with 1,000 gm.…”

Section: Resultsmentioning

confidence: 97%

Potentiation of Chlortetracycline in Laying Chickens

Robblee

Clandinin

1964

Poultry Science

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Lichttaglänge und Oxytetracyclin‐Blutplasmaspiegel bei Legehennen nach Verabreichung von Oxytetracyclin in therapeutischer Dosierung über das Futter

Kh¹,

Kw²,

Lüders³

1972

Zentralblatt für Veterinärmedizin Reihe B

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Summary Length of daylight and oxytetracycline plasma level in laying hens given therapeutic doses of oxytetracycline in the food Using the gel diffusion test, the plasma level of oxytetracycline was measured at intervals in laying hens given oxytetracycline in the food and receiving 9 and 17 hours of artificial lighting. When 700 ppm of OTC was given in the food it was only possible to reach and maintain a minimal plasma therapeutic level of 0.5 mcg./OTC/ml. over a period of several days by adding potentiating substances (terephthalic acid) to the food and reducing its calcium content. The largest amounts of OTC per unit of time were ingested by the laying hens before the end of a period of artificial illumination, independently of the length of the illuminated day. The maximal OTC plasma levels also occurred just before or after the end of a period of illumination. The ingestion of medicaments is limited by periods of illumination. One should take account of the effects of this illumination on the blood tissue levels when applying drugs therapeutically in the food and water. Résumé Durée d'illumination et taux de l'oxytétracycline dans le plasma sanguin chez des pondeuses, après administration d'oxytétracycline en doses thérapeutiques dans l'aliment On détermine à différents moments, à l'aide du test de diffusion en gélose, le taux d'oxytétracycline dans le plasma sanguin chez des pondeuses ayant ingéré librement de l'aliment contenant de l'oxytétracycline, pendant 9 et 17 heures d'illumination artificielle. Lorsque l'on administre 700 ppm de OTC par l'aliment, on n'aitteint et on ne maintient la valeur minimum de 0,5 mcg OTC/ml, considérée comme thérapeutiquement active, chez les animaux d'expérience, qu'en plusieurs jours et après adjonction de substances potentialisantes (acide téréphtalique) à l'aliment et réduction du calcium alimentaire. Les pondeuses ingèrent toujours les quantités de OTC les plus élevées par unite de temps avant la fin d'une période d'illumination artificielle, indépendante de la lumière du jour. On observe également les valeurs maximums de OTC dans le plasma sanguin dans le laps de temps avant ou après la fin d'une période d'illumination. L'ingestion des médicaments est limitée par les périodes d'illumination. Il faudrait tenir davantage compte des effets de cette limitation sur le taux sanguin et tissulaire, dans l'application thérapeutique de médicaments par l'aliment et l'eau d'abreuvage. Resumen Longitud de la luz dial y el nivel de oxitetraciclina en el plasma sanguíneo de gallinas ponedoras después de la administración de oxitetraciclina en dosis terapéuticas con el pienso En momentos diferentes se valoraron en la prueba de placas horadadas de agar los niveles del plasma sanguíneo de gallinas ponedoras, las cuales se iluminaban nueve y 17 horas con luz artificial, pudiendo ingerir oxitetraciclina libremente con el pienso. Al administrar 700 ppm de OTC a través del pienso, el valor mínimo en plasma sanguíneo terapéuticamente activo admitido de 0,5 mcg OTC/ml en los animales de ens...

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The Effect of Feeding Various Levels of Calcium and Phosphorus on the Performance and Absorption of Chlortetracyline of Caged Layers

Cited by 3 publications

References 7 publications

The Effects of Low Levels of Calcium in the Diet of Laying Chickens

The Effects of Low Levels of Calcium in the Diet of Laying Chickens

Potentiation of Chlortetracycline in Laying Chickens

Lichttaglänge und Oxytetracyclin‐Blutplasmaspiegel bei Legehennen nach Verabreichung von Oxytetracyclin in therapeutischer Dosierung über das Futter

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