The Effect of Fentanyl on the Emergence Characteristics After Desflurane or Sevoflurane Anesthesia in Children

Cohen, Ira Todd; Finkel, Julia C.; Hannallah, Raafat S.; Hummer, Kelly A.; Patel, Kantilal M.

doi:10.1097/00000539-200205000-00023

Cited by 141 publications

(102 citation statements)

References 16 publications

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“…16,17 Our results are consistent with these findings despite the fact that these previous studies differed in their use of nitrous oxide for anesthesia induction and maintenance. Nevertheless, few studies have compared anesthesia emergence times between desflurane and sevoflurane after volatile induction in adults.…”

Section: Discussionsupporting

confidence: 90%

“…This is most likely due to the young age of the participants in prior studies, which prevented precise measurements of recovery times. 16,17 The times in our study from discontinuation of volatile anesthetics to orientation to the patients' full name, date, and place were significantly shorter in the desflurane group than in the sevoflurane group, which suggests that changing from sevoflurane to desflurane permits faster recovery than sevoflurane anesthesia, even after sevoflurane induction. In addition, the time trend in recovery events differed between the two groups.…”

Section: Discussionmentioning

confidence: 66%

See 1 more Smart Citation

Effects of changing from sevoflurane to desflurane on the recovery profile after sevoflurane induction: a randomized controlled study

Mikuni

Harada

Yakushiji

et al. 2015

Can J Anesth/J Can Anesth

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 66%

Effects of changing from sevoflurane to desflurane on the recovery profile after sevoflurane induction: a randomized controlled study

Mikuni

Harada

Yakushiji

et al. 2015

Can J Anesth/J Can Anesth

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“…Fentanyl 2.5 lg.kg À1 has been shown to reduce the incidence of severe ED without a delay in emergence [35,36]. Kim ] following desflurane anaesthesia [19].…”

Section: Time (Min)mentioning

confidence: 99%

A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children

et al. 2015

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Emergence delirium is a common problem in children recovering from general anaesthesia. We performed a study comparing emergence characteristics in 100 patients who were randomly allocated to receive either 0.3 lg.kg À1 dexmedetomidine, 1 mg.kg À1 propofol or saline 0.9% and undergoing infra-umbilical surgery. The Pediatric Anesthesia Emergence Delirium scale was used to grade emergence delirium. Emergence delirium occurred in 9.4% of children in the dexmedetomidine group compared with 13.9% in the propofol group and 40.6% in the control group (p = 0.004). In the dexmedetomidine group, sedation occurred in 62.5% of children at 10 min after transfer to the recovery area, compared with 44.4% in the propofol group and 12.5% in the control group (p = 0.010). We conclude that dexmedetomidine significantly reduced the incidence of emergence delirium but this was at the expense of a greater incidence of sedation in the recovery period.

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“…Dong et al, found that intraoperative remifentanil decreased the incidence of ED in children undergoing adenotonsillectomy [60]. Fentanyl, given either IV 2.5 μg/kg or intranasally 2 μg/kg during moderately painful surgery, has also been shown to decrease emergence agitation in children [61][62][63][64]. Bong et al, confirmed the preventative effects of fentanyl and further identified a lack of fentanyl as an independent risk factor for ED [34].…”

Section: Nsaids and Opioidsmentioning

confidence: 99%

Emergence delirium: a narrative review

Viswanath¹,

Kerner²,

Jean³

et al. 2015

J Anesthesiol Clin Sci

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Emergence delirium (ED) is a post-surgical phenomenon associated with an increase in morbidity, mortality and resource utilization. A systematic review of all current treatment modalities for this condition is imperative given its prevalence during postoperative recovery. This review scrutinizes a number of studies in order to better characterize ED, with particular focus paid to the condition's etiology, associated risk factors, prevention and management. Extensive studies have been conducted on the pediatric population with little attention directed towards the adult and geriatric age groups. Despite this, evidence-based protocols for the management of this condition are still lacking for all age groups. In order to ensure cost effective management and improved safety outcomes for ED, future research should establish and further improve upon screening protocols to identify at risk patients, in addition to formulating a standardized treatment regimen for perioperative patients at risk. Keywords: Emergence delirium, anesthesia recovery period, anesthetic issues and peri-operative care, perioperative complications, preoperative evaluation and anesthesia risk, complications in the post anesthesia care unit

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The Effect of Fentanyl on the Emergence Characteristics After Desflurane or Sevoflurane Anesthesia in Children

Abstract: The concurrent use of fentanyl in a dose of 2.5 microg/kg in children receiving desflurane or sevoflurane results in a low incidence of emergence agitation. Desflurane allows for a more rapid emergence and recovery than sevoflurane.

Cited by 141 publications

References 16 publications

Effects of changing from sevoflurane to desflurane on the recovery profile after sevoflurane induction: a randomized controlled study

Effects of changing from sevoflurane to desflurane on the recovery profile after sevoflurane induction: a randomized controlled study

A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children

Emergence delirium: a narrative review

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