“…Thirteen trials evaluated the efficacy of varying fluoride (F) vehicles: (i) toothpaste as 1500 ppm NaF, 1250 ppm Amine F, 0.243% NaF/Silica, 1450 ppm sodium‐monoflurophosphate (MFP) 1450 ppm, 5000 ppmF, 0.4% stannous F/calcium pyrophosphate ; (ii) varnish as 5% NaF, 6% NaF + 6% CaF, and 0.1% F ; (iii) gel as 1.23% acidulated‐phosphate‐fluoride (APF), 1% NaF neutral (4500 ppm), and 4000 ppm Amine F ; and (iv) mouthrinse as 50 ppm NaF (Willmot). Sample sizes for the trials ranged from 15 to 3093 subjects and were conducted between 2 weeks and 4.02 years (loss to follow‐up ranged from 0% to 54.3%).…”