The effect of hydroalcoholic Berberis integerrima fruits extract on the lipid profile, antioxidant parameters and liver and kidney function tests in patients with nonalcoholic fatty liver disease

Abstract

Graphical abstract

The Effects of Berberis integerrima Fruit Extract on Glycemic Control Parameters in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Clinical Trial

“…Although in the present study B. integerrima did not have a significant effect on body weight, BMI, and blood pressure in diabetic patients, the weight loss and hypotensive effects of Berberis plants have been shown previously [ 30 , 31 ]. Furthermore, barberry is used in the traditional medicine to treat hypertension.…”

Phytochemical profiling and antioxidant potential of Daphne mucronata Royle and action against paracetamol-induced hepatotoxicity and nephrotoxicity in rabbits

“…The severity of the damage in terms hepatotoxicity and nephrotoxicity induced by paracetamol was evident from an increase in the serum levels of the lipid peroxidation indicator; malondialdehyde and decreased levels of GSH and TAC (which serves as indices of antioxidant status). Significant decreases in GSH and TAC levels have also been observed in the liver, kidney, and blood of patients with liver disease compared to controls in a reported study ( Afsharinasab et al, 2020 ). In recent years, a large number of plants have been tested to eradicate the liver damage caused by paracetamol in animal models, and the bioactive compounds responsible for alleviating oxidative stress have been isolated ( Meharie et al, 2020 ).…”

Cost-effectiveness of dietary supplement ingredients versus generic statins for LDL reduction

“…Baseline data was extracted from within systematic reviews providing the evidence base for LDL lowering with each assessed product for the RCTs that compared single active ingredient products versus placebo as displayed in Supplemental Table 1. 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 We calculated the pooled weighted mean differences (MD) for LDL in the active groups versus the placebo groups over varying follow-up periods ranging from 8 to >24 weeks with negative numbers representing greater LDL reductions as displayed in Fig. 1 .…”