The effect of ionising radiation on testosterone binding globulin characteristics: Correction of the protein' parameters by lipid polyene complexes of fungus<i>Laetiporus sulfureus</i>

Popoff, Eugene H.; Kapich, Alexander N.

doi:10.3109/09553000903422548

Cited by 4 publications

(2 citation statements)

References 35 publications

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“…Liu et al [75] and Michael and Amer [76] found that the level of testosterone was decreased after whole-body irradiation dose of 4 and 5 Gy due to alterations in DNA-single strand break, cell apoptosis and oxidative stress. Popoff and Kapich [77] observed a positive correlation between a decline in testosterone affinity and exposure to gamma irradiation. Also, Oi-Kano et al [78] reported that γ-irradiation exposure (6 Gy) resulted in a significant decline in testosterone concentration due to generation of free radicals.…”

Section: Discussionmentioning

confidence: 95%

The Antioxidant Role of Mulberry (Morus alba L.) Fruits in Ameliorating the Oxidative Stress Induced in γ-Irradiated Male Rats

Hamzaa¹

2012

Biochem Anal Biochem

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Materials and Methods Materials and plant preparation Standard commercial rodent diet and fresh purple-colored mulberry fruits were purchased from the local market (Cairo, Egypt). All berries were dried at 70°C for 4 days and grounded to powder [17]. Radiation facility Whole body gamma irradiation of rats was performed using a Canadian gamma cell-40, (137Cs) housed at the National Center for Radiation Research and Technology (NCRRT), Cairo, Egypt. The dose rate was 0.43 Gy/min at the time of the experiment. Rats were exposed to fractionated dose of 7.5 Gy γ-irradiation administered as 2.5 Gy, every other day. Determination of total phenolic compounds The concentration of total phenolic compound was measured by a modified Follin-Ciocalteu colorimetric method [18]. Briefly, a sample diluted was added to a test tube containing 1.58 mL of distilled water. Folin-Ciocalteu reagent of 100 μL was added, and the tube was stirred and allowed to stand at room temperature for 8 min. 300 μL of Na 2 CO 3 (7%, w/v) was added to the mixture and the absorbance was measured at 765 nm, after 120 min at room temperature, using a spectrophotometer. The results were expressed as milligram of Gallic Acid Equivalents (GAE) per gram fresh matter of fruit (mg GAE/ g fruit). Determination of antioxidant activity by the 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) DPPH assay was determined by previously method described

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Section: Discussionmentioning

confidence: 95%

The Antioxidant Role of Mulberry (Morus alba L.) Fruits in Ameliorating the Oxidative Stress Induced in γ-Irradiated Male Rats

Hamzaa¹

2012

Biochem Anal Biochem

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“…Also, Popoff and Kapich [73] found a positive correlation between a decline in testosterone affinity and exposure to gamma irradiation. In addition, the lowering effect of γ-irradiation exposure on insulin level was observed due to production of free radicals that induced oxidative stress resulted in reduction in insulin secretion and DNA damage [3].…”

Section: Essential Oil %mentioning

confidence: 91%

Using of Coffee and Cardamom Mixture to Ameliorate Oxidative Stress Induced in γ-irradiated Rats

Hamzaa¹,

Osman²

2012

Biochem Anal Biochem

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Human exposure to ionizing radiation induced overproduction of free radicals leading to oxidative stress. This study aims to evaluate the possibility of using of coffee and cardamom mixture, as natural antioxidant compounds, to ameliorate the damage effect of oxidative stress. Phenolic contents in coffee and essential oils in cardamom were identified by using HPLC chromatography and GC/MS analysis. Four groups of adult male rats were used; the control group (A), the second group (B) received orally mixture extract of coffee and cardamom (60 mg/100g body weight) for 8 weeks, the third group (C) γ-irradiated (6 GY) and the fourth group (D) received orally mixture extract for 8 weeks and exposed to γ-irradiation at the 4th week. The results revealed that the administration of mixture extract of coffee and cardamom were significantly reduced the damage effect induced by γ-irradiation exposure. Accordingly, it could be concluded that, via the adjustment of the antioxidant status, decreasing the releasing of lipid peroxides and the subsequent amending of different biochemical parameters and some hormones, mixture of coffee and cardamom could ameliorate the hazardous effects of oxidative stress induced by irradiation exposure.

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The low dose gamma ionising radiation impact upon cooperativity of androgen-specific proteins

Filchenkov

Popoff

Наумов

2014

Journal of Environmental Radioactivity

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The effect of ionising radiation on testosterone binding globulin characteristics: Correction of the protein' parameters by lipid polyene complexes of fungusLaetiporus sulfureus

Cited by 4 publications

References 35 publications

The Antioxidant Role of Mulberry (Morus alba L.) Fruits in Ameliorating the Oxidative Stress Induced in γ-Irradiated Male Rats

The Antioxidant Role of Mulberry (Morus alba L.) Fruits in Ameliorating the Oxidative Stress Induced in γ-Irradiated Male Rats

Using of Coffee and Cardamom Mixture to Ameliorate Oxidative Stress Induced in γ-irradiated Rats

The low dose gamma ionising radiation impact upon cooperativity of androgen-specific proteins

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