The effect of leek (Allium iranicum (Wendelbo)) leaves extract cream on hemorrhoid patients: A double blind randomized controlled clinical trial

Mosavat, Seyed Hamdollah; Ghahramani, Leila; Sobhani, Zahra; Haghighi, Ehsan Rahmanian; Chaijan, Mahsa Rostami; Heydari, Mojtaba

doi:10.1016/j.eujim.2015.08.008

Cited by 29 publications

(15 citation statements)

References 20 publications

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“…6,7 Treatment lines for hemorrhoids are discussed as conservative approaches such as dietary fiber and oral fluids, rest, and nonsteroidal anti-inflammatory drugs as well as surgical techniques associated with degrees of complication. 4,8 The first known description about hemorrhoids dates back to nearly 1700 BC, when Egyptians wrote on papyrus about the treatment of this disease. In the history of medicine, other traditional medical systems have discussed about hemorrhoids and related treatment.…”

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confidence: 99%

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An Evidence-Based Study on Medicinal Plants for Hemorrhoids in Medieval Persia

Hashempur

Khademi

Rahmanifard

et al. 2017

J Evid Based Complementary Altern Med

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Hemorrhoids is one of the most common gastrointestinal diseases. There are several therapeutic options associated with some complications. Therefore, researchers look for traditional medicines as a potential resource for introduction of new natural drugs. The current study reports an evidence-based review of herbal remedies for hemorrhoids in traditional Persian medicine. A comprehensive survey about hemorrhoids on the most important manuscripts of traditional Persian medicine was done. Then, scientific data banks were searched for possible related properties of each herb in the conventional medicine. We reported some historical aspects of traditional Persian medicine view on classification, examination, and predisposing factors of hemorrhoids. In addition, we have reported 105 medicinal plants belonging to 51 families. More than half of the reported herbs exhibited anti-inflammatory and analgesic effects. Although lack of human studies regarding the mentioned herbs is noted, positive results from experimental findings can be considered for new drug discovery supported by traditional and medieval experiences.

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confidence: 99%

“…Treatment lines for hemorrhoids are discussed as conservative approaches such as dietary fiber and oral fluids, rest, and nonsteroidal anti-inflammatory drugs as well as surgical techniques associated with degrees of complication. 4,8…”

mentioning

confidence: 99%

An Evidence-Based Study on Medicinal Plants for Hemorrhoids in Medieval Persia

Hashempur

Khademi

Rahmanifard

et al. 2017

J Evid Based Complementary Altern Med

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“…For example, according to the Canon of Medicine written by Avicenna ( Ibn-e-Sina ) ( ad 980-1037). 6 It can be used for headache and some neural and gastrointestinal diseases. 7 Also, Aghili in The Storehouse of Medicaments (written in ad 1772) 8 has recommended Nasrin as a tonic for heart and brain, and for treatment of some hepatic disorders.…”

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confidence: 99%

Antidiabetic and Antihyperlipidemic Effects of Ethanol Extract of Rosa canina L. fruit on Diabetic Rats

Taghizadeh

Rashidi

Taherian

et al. 2016

J Evid Based Complementary Altern Med

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Rosa canina L. (Rosaceae) has been traditionally used as a medicinal plant. This study was undertaken to evaluate the antidiabetic and antihyperlipidemic effects of Rosa canina fruit extract in streptozotocin induced diabetic rats. The results showed oral administration of Rosa canina fruit extract significantly ameliorated the high levels of blood glucose compared with the control group. Serum triglyceride levels significantly decreased by the administration of Rosa canina extract compared with control. Histopathological examinations showed that the Rosa canina extract improved islets necrotic and regenerated pancreatic islet cells. Rosa canina extract has the antihyperglycemic and antihyperlipidemic effects in streptozotocin-induced diabetic rats.

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“…Notably, many experts and scholars have carried out detailed studies on traditional Chinese medicine in replacing antibiotics to treat hemorrhoids in China. [ 19 – 21 ] Wu et al proposed the use of Liuhe Pill Ointment to prevent infection in patients with hemorrhoids, and the results showed that, compared to the control group, the score of wound edema and pain, the length of hospital stay and wound healing time in the study group treated with Liuhe Pill Ointment were shortened. [ 20 ] Shi et al used Blood-cooling Rehmannia Soup as the main drug for hemorrhoids treatment, and showed that the score of anal distension after 14day treatment was significantly lower while the score of the life quality was higher than that after 7day of treatment.…”

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confidence: 99%

Clinical study of herbal mixture “Diding Oral Medicine” as an alternative to preventative antibiotics in perioperative hemorrhoids

Gao¹,

Cheng²,

Liu³

et al. 2021

Medicine

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To study the clinical effects of Diding Oral Medicine as an alternative to preventative antibiotics in perioperative hemorrhoids. From August 2017 to February 2018, a total of 214 patients who were treated with external exfoliation and internal ligation of mixed hemorrhoids in our hospital were divided into the control group and experimental group by way of stratified random (107 cases in each group). Patients in the control group were given antibiotics preventatively before operation, while patients in the experimental group took Diding Oral Medicine before operation, and the white blood cell count, neutrophil count, wound recovery, pain score, anal bulge score, and pathogen culture of wound secretions were compared between the 2 groups. There was no significant difference in white blood cell count and neutrophil count between both groups before and after operation ( P > .05). The wound seepage score, wound edema score, and wound area score in the experimental group were lower than those in the control group, and the wound healing in the experimental group was shorter than that in the control group (all P < .05). The pain score and anal bulge score of the experimental group were decreased significantly compared to the control group ( P < .05). In addition, the detection rate of pathogenic bacteria in the experimental group was downregulated significantly compared to the control group ( P < .05). The Diding Oral Medicine has prominent bacteriostatic and antibacterial effects on patients with hemorrhoids during perioperative period, and promotes wound healing, reduces pain stress, and anal bulge.

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The effect of leek (Allium iranicum (Wendelbo)) leaves extract cream on hemorrhoid patients: A double blind randomized controlled clinical trial

Cited by 29 publications

References 20 publications

An Evidence-Based Study on Medicinal Plants for Hemorrhoids in Medieval Persia

An Evidence-Based Study on Medicinal Plants for Hemorrhoids in Medieval Persia

Antidiabetic and Antihyperlipidemic Effects of Ethanol Extract of Rosa canina L. fruit on Diabetic Rats

Clinical study of herbal mixture “Diding Oral Medicine” as an alternative to preventative antibiotics in perioperative hemorrhoids

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