The Effect of Light on Quality of Sleep and Life in Breast Cancer Patients

Abstract

ÖzObjective: In Obesity Hypoventilation syndrome (OHS), pulmonary hypertension (PH) is an important morbidity and mortality reason compared to pure Obstructive Sleep Apnea syndrome (OSAS). However, few studies are available in the literature about this subject. For this reason, we evaluated OHS and pure OSAS cases in our study from the point of right heart-related echocardiographic parameters and PH. Materials and Methods: Obese [body mass index (BMI) >30 kg/m 2 ] cases diagnosed by polysomnography were included in the study. The subjects were divided to two groups as OHS and pure OSAS. OHS criteria were defined as obesity (BMI >30 kg/m 2 ) and for another reason unexplained (neuromuscular, chest wall, restrictive or obstructive pulmonary diseases) daytime hypercapnia (PaCO 2 >45 mmHg). Patients with severe hypothyroidism, renal and heart insufficiency, cardiac drug anamnesis were not included in the study. Transthoracic echocardiography was performed to all cases and those with left-heart pathology were excluded from the study. Systolic pulmonary artery pressure (PABs) >35 mmHg was accepted as PH. Results: Of the 115 cases studied (mean age: 49.3±10.6/year, female/ male: 53/62, BMI: 40.5±6.1 kg/m 2 ), 70 were pure OSAS and 45 were OHS. In the OHS group, PABs, right ventricular diameter and pulmonary velocities were significantly higher than the pure OSAS group (p=0.002, p=0.015, p=0.012, respectively). The frequency of PH in OHS was significantly higher than group with pure OSAS (48.8% vs. 17.1%, p<0.001). In the overall group, there was a positive correlation between PABs value and apnea-hypopnea index, OSAS phase, oxygen desaturation index, SpO 2 <90% elapsed time, and OHS presence (r=0. ) ve başka bir nedenle açıklanamayan (nöromüsküler hastalık, göğüs duvarı patolojileri, restriktif ve obstrüktif akciğer hastalıkları gibi) gündüz hiperkapnisi (PaCO 2 >45 mmHg) olarak tanımlanmıştır. Ciddi hipotiroidi, böbrek ve kalp yetmezliği, kardiyak ilaç anamnezi olanlar çalışmaya dahil edilmedi. Olgulara transtorasik ekokardiyografi yapıldı ve sol kalp patolojisi olanlar çalışma dışı bırakıldı. Sistolik pulmoner arter basıncı (PABs) >35 mmHg olması, PH olarak kabul edildi. Bulgular: Çalışmaya alınan 115 olgunun (ortalama yaş: 49,3±10,6/ yıl, kadın/erkek: 53/62, VKİ: 40,5±6,1 kg/m 2 ) 70'i saf OUAS, 45'i OHS idi. OHS grubunda PABs, sağ ventrikül çapı ve pulmoner velosite saf OUAS grubuna göre anlamlı olarak daha yüksekti (p=0,002, p=0,015, p=0,012). OHS grubunda, PH sıklığı saf OUAS grubuna göre anlamlı olarak daha fazlaydı (%48,8 ve %17,1, p<0,001). Genel grupta, PABs değeri ile apne-hipopne indeksi, OUAS ağırlığı, oksijen desaturasyon indeksi, SpO 2 <%90 geçen süre ve OHS varlığı arasında pozitif korelasyon vardı (sırasıyla; r=0,307, p=0,001; r=0,259, p=0,005; r=0,405, p<0,001; r=0,162, p<0,001; r=0,305 p=0,001). PABs ile ortalama ve minimum SpO 2 arasında negatif korelasyon vardı (sırasıyla r=-0,404, p<0,001; r=-0,344, p<0,001). Sonuç: OHS olgularında; PABs, sağ ventrikül çapı ve pulmoner velosite ve PH sı...

The effect of light therapy on sleep quality in cancer patients: a systematic review and meta-analysis of randomized controlled trials

“…These studies included a total of 451 participants, with 234 in the intervention group and 217 in the control group. Of these, five were conducted in the US ( 24 , 30 , 31 , 39 , 40 ), two in Turkey ( 41 , 42 ), one in Canada ( 43 ), and another one in the Netherlands ( 44 ). The average age of the participants in these studies was 55.32 years.…”

“…As shown, performance bias was the most common type of bias in these studies. Of the nine studies included in the systematic review, five had issues with blinding with four having definite and one possible risk ( 24 , 30 , 31 , 39 , 41 ). Given the design of these studies, it was likely that the blinding issue was more related to research personnel than the participants.…”

The Effect of the Bright White Light Application to Cancer Patients Receiving Palliative Care on Their Fatigue Level and Sleep Quality: A Randomized Control Trial

“…It was found in previous studies that the BWL source did not produce the same effect on sleep quality in treatment groups and that the BWL on cancer patients receiving palliative care had an effect on sleep quality. In a randomized controlled trial, Özkaraman et al (2018) applied BWL (10,000 lux) for 30 minutes a day for a week to breast cancer patients who reported low sleep quality and found that the patients in the treatment group had decreased sleep quality scores albeit not significantly (Özkaraman et al, 2018). They concluded that, unlike in this study, the BWL did not affect sleep quality.…”

Effect of Reiki Therapy on Quality of Life and Fatigue Levels of Breast Cancer Patients Receiving Chemotherapy

“…The study sample included patients who were between 18 and 54 years of age, who previously received a minimum of 1 course of adjuvant chemotherapy and would receive at least 3 more courses of treatment, who did not have a psychiatric diagnosis, and who obtained 1 to 10 points on the Piper Fatigue Scale. The study sample was determined using the power analysis, which was carried out based on fatigue and quality-of-life mean scores obtained from previous relevant studies 34,35 . As a result, 70 patients were included in the study, 35 for each group based on α = .05 error, 83.59% test power, and d = 0.899 effect size.…”

“…The study sample was determined using the power analysis, which was carried out based on fatigue and quality-of-life mean scores obtained from previous relevant studies. 34,35 As a result, 70 patients were included in the study, 35 for each group based on α = .05 error, 83.59% test power, and d = 0.899 effect size.…”