1962
DOI: 10.1097/00000542-196209000-00002
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The Effect of Methoxyflurane-Nitrous Oxide Anesthesia on Arterial pH, Oxygen Sturation, Pacco2 and Plasma Bicarbonate in Man

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Cited by 13 publications
(2 citation statements)
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“…Early studies by Campbell, Nunn and Peckett (1958) and Frurnin et al (1959) have indicated alveolar-arterial Po 3 gradients intermediate between normal values and those found in this study. Studies of arterial saturation during anaesthesia have shown lower levels than would be expected in conscious subjects at comparable minute volumes (Ikezono et al, 1959;Cole and Parkhouse, 1961;Dobkin and Song, 1962;Wakai, 1963;Conway and Payne, 1964).…”
Section: Discussionmentioning
confidence: 99%
“…Early studies by Campbell, Nunn and Peckett (1958) and Frurnin et al (1959) have indicated alveolar-arterial Po 3 gradients intermediate between normal values and those found in this study. Studies of arterial saturation during anaesthesia have shown lower levels than would be expected in conscious subjects at comparable minute volumes (Ikezono et al, 1959;Cole and Parkhouse, 1961;Dobkin and Song, 1962;Wakai, 1963;Conway and Payne, 1964).…”
Section: Discussionmentioning
confidence: 99%
“…Other evidence of arterial oxygen desaturation in premedicated patienits before surgery was obtained from a series of palpers puiblished between 1959 and 1962 'by Dobkin and his group who measured the arterial oxygen saturation in a 'total of 161 premedicated patients before ithe induction of anaeSthesia (Dobkin, 1959;Dobkin, Drummond and Perkin, 1959; Dobbk'in, Jdhnston and Skinner, 1959;Dobkin andByles, 1962a, 1962b;Dobkin and Song, 1962). The mean arterial oxygen saturation of 90.7% derived from these determinations implied a significant degree of impaired oxygenation ascribed 'by Dobkin and 'his colleagues to 'the centtral depressanrt effect of the narcotic drugs included in the premedication.…”
Section: Effect Of Premedicationmentioning
confidence: 99%