The effect of mifepristone on estrogen receptors following treatment with medroxyprogesterone acetate in cultured human endometrial explants

Modulation of HOXA10 and other markers of endometrial receptivity by age and human chorionic gonadotropin in an endometrial explant model

“…Furthermore, continued cell proliferation was confirmed by stromal staining of Ki-67, confirming tissue viability of the explant at 24 hours. Previous studies using the endometrial explant system have confirmed tissue viability for 3-5 days (15,16), lending support to the use of this model for the study of endometrial receptivity. Its advantage in maintaining the possibility for interactions between the glands, stroma, and epithelium allows for the study of a more physiologic endometrial response, one in which the paracrine role can be taken into account.…”