The effect of mineral trioxide aggregate on the production of growth factors and cytokine by human periodontal ligament fibroblasts

Kwon, Ji Y.; Lim, S. Sam; Baek, Seung Ho; Bae, Kwang-Shik; Kang, Myung Hoe; Lee, Woo-Cheol

doi:10.5395/jkacd.2007.32.3.191

Cited by 5 publications

(3 citation statements)

References 29 publications

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“…Since the clinical indications of Bioaggregate are the same as those of MTA, it might be helpful to compare this new material with MTA, which has already been studied and proven to be effective and biocompatible over the past few years. [13][14][15] This study examined the biocompatibility of BioAggregate compared to white ProRoot MTA on the cells derived from human dental pulp and periodontial tissue.…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Chung

Kim

Shin

2010

J Korean Acad Conserv Dent

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Objectives: This study was performed to investigate the biocompatibility of newly introduced Bioaggregate on human pulp and PDL cells. Materials and Methods: Cells were collected from human pulp and PDL tissue of extracted premolars. Cell culture plate was coated either with Bioaggregate or white MTA, then the same number of cells were poured to cell culture dishes. Cell attachment and growth was examined under a phase microscope after 1,3 and 7 days of seeding. Cell viability was measured and the data was analyzed using Student t-test and one way ANOVA. Results: Both types of cells used in this study were well attached and grew healthy on Bioaggregate and MTA coated culture dishes. No cell inhibition zone was observed in Bioaggregate group. There was no statistical difference of viable cells between bioaggreagte and MTA groups. Conclusions: Bioaggregate appeared to be biocompatible compared with white MTA on human pulp and PDL cells.

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Section: Introductionmentioning

confidence: 99%

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Chung

Kim

Shin

2010

J Korean Acad Conserv Dent

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“…4 Kwon et al reported that MTA inhibits the stimulatory function of growth factors on granulation tissue formation and promotes the healing process modulated by bone-remodeling cells. 5 MTA extracts were reported to be more biocompatible with human osteogenic sarcoma cells than calcium hydroxide based material and eugenol based material. 6 In an in vitro study assessing cell viability on the surface of MTA, MTA showed low cytotoxicity similar to control group.…”

Section: Introductionmentioning

confidence: 99%

“…3 The biocompatibility of MTA has been assessed in many studies. [3][4][5][6][7][8][9][10][11][12][13][14] Calcium hydroxide which is biocompatible with tissue, is the main compound released by MTA in water. 3 The results of an in vitro study showed that MTA was less toxic than amalgam, SuperEBA and IRM.…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Jeong

Bae

et al. 2010

J Korean Acad Conserv Dent

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Objectives:The purpose of the present in vitro study was to evaluate the biocompatibility of mineral trioxide aggregate (MTA) mixed with glass ionomer cement (GIC), and to compare it with that of MTA, GIC, IRM and SuperEBA. Materials and Methods: Experimental groups were divided into 3 groups such as 1 : 1, 2 : 1, and 1 : 2 groups depending on the mixing ratios of MTA powder and GIC powder. Instead of distilled water, GIC liquid was mixed with the powder. This study was carried out using MG-63 cells derived from human osteosarcoma. They were incubated for 1 day on the surfaces of disc samples and examined by scanning electron microscopy. To evaluate the cytotoxicity of test materials quantitatively, XTT assay was used. The cells were exposed to the extracts and incubated. Cell viability was recorded by measuring the optical density of each test well in reference to controls. Results: The SEM revealed that elongated, dense, and almost confluent cells were observed in the cultures of MTA mixed with GIC, MTA and GIC. On the contrary, cells on the surface of IRM or SuperEBA were round in shape. In XTT assay, cell viability of MTA mixed with GIC group was similar to that of MTA or GIC at all time points. IRM and SuperEBA showed significantly lower cell viability than other groups at all time points (p < 0.05).

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Osteo/odontogenic Differentiation of Human Mesenchymal Stem Cells with Platelet-rich Plasma and Mineral Trioxide Aggregate

Vanka

Vishwakarma

Bhat

et al. 2019

The Journal of Contemporary Dental Practice

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The effect of mineral trioxide aggregate on the production of growth factors and cytokine by human periodontal ligament fibroblasts

Cited by 5 publications

References 29 publications

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Biocompatibility of experimental mixture of mineral trioxide aggregate and glass ionomer cement

Osteo/odontogenic Differentiation of Human Mesenchymal Stem Cells with Platelet-rich Plasma and Mineral Trioxide Aggregate

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