The Effect of Mouthrinse Containing Calcium Glycerophosphate on the Chemical Composition and Development of Plaque in Humans

Wycoff, Samuel J.; Morris, Merle E.; Newbrun, Ernest

doi:10.1177/00220345800590010401

Cited by 6 publications

(5 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The levels of calcium and phosphorus in the con trol group were in the same range as those reported by other investigators [Dawes and Jenkins, 1962;Ashley, 1975;Schamschula et al, 1977;Kleinberg et al, 1971], The increases of calcium and phosphorus induced by calcium lactate were more pronounced than those ob tained with calcium glycerophosphate used either in a mouthrinse [Wycoff et al, 1980], in tablets [Brook et al, 1975], or as a dietary supplement [Bowen, 1972]. This might be due to the relatively high concentration of calcium lactate in the rinse.…”

Section: Discussionsupporting

confidence: 83%

See 1 more Smart Citation

Effect of a Mouthrinse Containing Calcium Lactate on the Formation and Mineralization of Dental Plaque

Hoeven¹,

Schaeken²,

Creugers³

1989

Caries Res

View full text Add to dashboard Cite

In this study, a mouthrinse containing calcium lactate was tested for its effect on the accumulation of dental plaque and on the concentrations of calcium and phosphorus therein. Human volunteers rinsed four times per day with a calcium lactate (165 mmol/l) solution for 1 week. Plaque samples, collected 16 h after the last rinse, were analyzed chemically. Calcium lactate rinses had no effect on the plaque score, but resulted in approximately twofold increases of calcium and phosphorus in plaque. The incorporation of monofluorophosphate (5 mmol/l) into the rinsing solution failed to show any significant influence on calcium, phosphorus, and fluoride levels in plaque. Increased mineral deposition in the plaque may provide an explanation for the reduced caries development earlier observed in rats fed a diet containing calcium lactate.

show abstract

Section: Discussionsupporting

confidence: 83%

“…In a first approach, calcium lactate was applied in a mouthrinse, and the amounts of calcium and phos phorus in plaque samples were measured after 1 week of rinsing. As it cannot be ruled out that calcium lac tate affects bacterial metabolism [Kato et al, 1987] or plaque accumulation [Wycoff et al, 1980], the amount of plaque was also estimated. …”

mentioning

confidence: 99%

Effect of a Mouthrinse Containing Calcium Lactate on the Formation and Mineralization of Dental Plaque

Hoeven¹,

Schaeken²,

Creugers³

1989

Caries Res

View full text Add to dashboard Cite

show abstract

“…Even topical applications of sodium fluoride (2%) were not able to inhibit these changes [ 101 ]. Another study determined the accumulation of CGP in the dental plaque by having three different mouthrinse-interventions: (1) No CGP, (2) 0.5% CGP and (3) 1.5% CGP [ 102 ]. The concentration of phosphate was significantly greater in the plaque in (3) compared to (1), indicating a higher potential for buffering acidic attacks [ 102 ].…”

Section: Calcium Phosphates Used In Oral Carementioning

confidence: 99%

Overview of Calcium Phosphates used in Biomimetic Oral Care

Meyer¹,

Amaechi²,

Fabritius³

et al. 2018

TODENTJ

View full text Add to dashboard Cite

Background:The use of biomimetic agents is an emerging field in modern oral care. Promising biomimetic substances for such applications are calcium phosphates, because their chemical composition is very similar to that of the mineral phase in human teeth, especially of natural enamel. Examples for their application include the remineralization of early caries lesions and repair of small enamel defects.Objective:This review provides an interdisciplinary view on calcium phosphates and their applications in biomimetic oral care. The aim of this work is to give an overview of in vivo and in situ studies comparing several calcium phosphates in preventive dentistry that can be used as a knowledge base for the development of innovative alternative oral care concepts.Methods:Books, reviews, and original research papers with a focus on in vivo and in situ studies were included. The databases PubMed® and SciFinder® were used for literature search. Calcium phosphates that are frequently utilized in oral care products are covered in this review and were used as search terms alone and together with the following key words: in vivo, in situ, caries, clinical study, and remineralization. From 13,470 studies found, 35 studies complied with the inclusion criteria and were used for this review.Results:Published in vivo and in situ studies demonstrate calcium phosphates’ potential in enamel remineralization. However, more studies are needed to further substantiate existing results and to extend and refine the application of calcium phosphates in modern oral care.Conclusion:Calcium phosphates represent an innovative biomimetic approach for daily oral care because of their high similarity to natural enamel that will broaden the range of future treatments in preventive dentistry.

show abstract

“…Esse efeito tampão pode, ainda, ser devido a um aumento no conteúdo de fósforo na placa dentária, pois o uso de dentifrícios com CaGP aumentou as concentrações de íons de Ca e P no biofilme (52,53).…”

Section: Erosão Dentáriaunclassified

Avaliação do efeito preventivo do verniz contendo glicerofosfato de cálcio frente a desafios cariogênicos e erosivos

Carvalho¹

View full text Add to dashboard Cite

show abstract

The Effect of Mouthrinse Containing Calcium Glycerophosphate on the Chemical Composition and Development of Plaque in Humans

Cited by 6 publications

References 10 publications

Effect of a Mouthrinse Containing Calcium Lactate on the Formation and Mineralization of Dental Plaque

Effect of a Mouthrinse Containing Calcium Lactate on the Formation and Mineralization of Dental Plaque

Overview of Calcium Phosphates used in Biomimetic Oral Care

Avaliação do efeito preventivo do verniz contendo glicerofosfato de cálcio frente a desafios cariogênicos e erosivos

Contact Info

Product

Resources

About