The Effect of Nutrient Intake on Bone Mineral Status in Young Adults: The Northern Ireland Young Hearts Project

Neville, Charlotte; Robson, Paula J.; Murray, Liam; Strain, JJ; Twisk, Jos W. R.; Gallagher, Alison M.; McGUINNESS, M C L; Cran, G. W.; Ralston, Stuart H.; Boreham, Colin

doi:10.1007/s00223-001-1023-0

Cited by 39 publications

(40 citation statements)

References 24 publications

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“…It should be noted that the PIXI is not meant as a clinical evaluation tool and should not be used as such. Furthermore, forearm DXA is a sensitive site to detect improvements in BMD (2,5,6) and has demonstrated relationships with body composition in children (16) and adults (17). Therefore, the validity of PIXI-based BMD assessments in young children could have important implications for pediatric bone research.…”

Section: Discussionmentioning

confidence: 99%

“…DXA devices measure BMD in the whole body, spine, hip, and forearm, as well as assess body composition (1) and have been used successfully in children aged 2e5 yr (2e4). These sites are proven to respond to changes in nutrition (2,5,6). Although the International Society for Clinical Densitometry (7) recommends that lumbar spine and whole body scans be preferentially used in clinical pediatrics (5e19 yr), there are no guidelines for population assessments in healthy younger children.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bone Mineral Density Measured by a Portable X-ray Device Agrees With Dual-Energy X-ray Absorptiometry at Forearm in Preschool Aged Children

Hazell

Vanstone

Rodd

et al. 2013

Journal of Clinical Densitometry

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bone Mineral Density Measured by a Portable X-ray Device Agrees With Dual-Energy X-ray Absorptiometry at Forearm in Preschool Aged Children

Hazell

Vanstone

Rodd

et al. 2013

Journal of Clinical Densitometry

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“…However, this theory remains to be proven and the supporting evidence for an 'optimum' Ca/P ratio is lacking. Neville et al (2002) found a significant positive relationship between lumbar spine BMD and Ca/P ratio in young adult males, and Whiting et al (2002) showed that P was a significant positive predictor of whole body and lumbar spine BMD in men aged 39-42 y. A further study by Teegarden et al (1998) showed that whole body and spine BMC and BMD were positively related to P intake and Ca/P ratio.…”

Section: Bone Turnover In Adolescents F Ginty Et Almentioning

confidence: 90%

Effects of usual nutrient intake and vitamin D status on markers of bone turnover in Swiss adolescents

et al. 2004

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Objective: To evaluate the effects of nutrient intake and vitamin D status on markers of type I collagen formation and degradation in adolescent boys and girls. Design: Cross-sectional study. Setting: Canton of Vaud, West Switzerland. Subjects: A total of 92 boys and 104 girls, aged 11-16 y. Data were collected on height, weight, pubertal status (self-assessment of Tanner stage), nutrient intake (3-day dietary record) and fasting serum concentration of 25-hydroxyvitamin D (25OHD), and markers of collagen formation (P1NP) and degradation (serum C-terminal telopeptides: S-CTX). Results: Tanner stage was a significant determinant of P1NP in boys and girls and S-CTX in girls. Of the nutrients examined, only the ratio of calcium to phosphorus (Ca/P) was positively associated with P1NP in boys, after adjustment for pubertal status. 25OHD decreased significantly at each Tanner stage in boys. Overall, 15% of boys and 17% of girls were identified as being vitamin D insufficient (serum 25OHD o30 nmol/l), with the highest proportion of insufficiency at Tanner stage 4-5 (29%) in boys and at Tanner stage 3 (24%) in girls. A significant association was not found between 25OHD and either bone turnover marker, nor was 25OHD insufficiency associated with higher concentrations of the bone turnover markers. Conclusions: The marked effects of puberty on bone metabolism may have obscured any possible effects of diet and vitamin D status on markers of bone metabolism. The mechanistic basis for the positive association between dietary Ca/P ratio and P1NP in boys is not clear and may be attributable to a higher Ca intake per se, a critical balance between Ca and P intake or higher dairy product consumption. A higher incidence of vitamin D insufficiency in older adolescents may reflect a more sedentary lifestyle or increased utilisation of 25OHD, and suggests that further research is needed to define their requirements.

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“…Higher educational levels might indirectly influence bone health because individuals may have better knowledge and behaviors [17,18]. Higher educational levels may also be related to better nutrition and health during childhood and adolescence, when peak bone mass is attained [6,19,20]. In one study, Chinese postmenopausal women with higher educational levels were found to be taller and their age at menarche, an important factor for peak bone mass, was younger than that of less educated women [6].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Socioeconomic Position on Bone Health Among Koreans by Gender and Menopausal Status

et al. 2012

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While studies suggest that socioeconomic position (SEP) influences bone health and risk of osteoporotic fracture in postmenopausal women, few studies have simultaneously examined gender and menopause differences as they relate to SEP and bone health. Here, we investigated the relationship between SEP and bone mineral density (BMD) among Korean men, premenopausal women, and postmenopausal women using the BMD data set (n = 9,995) of the Korean National Health and Nutrition Examination Survey IV. The relationship between SEP and BMD was estimated using analysis of covariance (ANCOVA); adjustments were made for age and body mass index (BMI) in the multivariate models. The relationship between SEP and osteoporosis prevalence was estimated using logistic regression. Relative index of inequality (RII) in osteoporosis was estimated using log-binomial regression. ANCOVA (adjusted for age and for age plus BMI) showed a significant positive association between SEP and BMD among men and postmenopausal women. Logistic regression showed a significant negative association between SEP and osteoporosis prevalence among men and postmenopausal women but not in premenopausal women. The RII, estimated by log-binomial regression, showed the impact of SEP on osteoporosis to be significant in men and postmenopausal women (p < 0.05) but not in premenopausal women. Overall, low SEP was associated with both low BMD and high risk of osteoporosis among men and postmenopausal women. Efforts to reduce the economic burden of morbidity and mortality from osteoporosis should target men and postmenopausal women with low SEP.

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The Effect of Nutrient Intake on Bone Mineral Status in Young Adults: The Northern Ireland Young Hearts Project

Cited by 39 publications

References 24 publications

Bone Mineral Density Measured by a Portable X-ray Device Agrees With Dual-Energy X-ray Absorptiometry at Forearm in Preschool Aged Children

Bone Mineral Density Measured by a Portable X-ray Device Agrees With Dual-Energy X-ray Absorptiometry at Forearm in Preschool Aged Children

Effects of usual nutrient intake and vitamin D status on markers of bone turnover in Swiss adolescents

The Effect of Socioeconomic Position on Bone Health Among Koreans by Gender and Menopausal Status

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