The effect of oral honey and pollen on postoperative intraabdominal adhesions

Effects of alpha lipoic acid on intra-abdominal adhesion: an experimental study in a rat model

“…[1,2,6,7] Similar results have been reported with oral ALA having an antioxidant effect1. Our aim in this study was to investigate the effect of ALA on adhesion formation when administered intraperitoneally in an experimental rat model.…”

“…Peritoneal adhesion formation was reported to decrease with the use of an antioxidant substance. [1,2] Our aim in this study was to investigate the effects of intraperitoneal administration of ALA, which has an antioxidant effect, on intra-abdominal adhesion formation.…”

“…Laparoscopic procedures are preferred to open surgery with the aim of reducing peritoneal trauma to prevent adhesions. [1][2][3] Pharmacological agents preventing fibrin formation such as tissue plasminogen activator and heparin, and barrier products such as seprafilm are also available, [1,2,8] although none of them can completely prevent intra-abdominal adhesion. Recent studies have shown increased oxidative stress during peritoneal recovery and a positive relationship between oxidative stress and adhesion severity.…”

“…[3] Postoperative adhesions can cause complications such as small bowel obstruction, chronic pelvic pain, and infertility that may affect an individual's quality of life. [2][3][4][5] Diken Allahverdi et al Effects of alpha lipoic acid on intra-abdominal adhesion: an experimental study in a rat model fects in intra-abdominal adhesion formation. However, we did not come across any other study using the oral form to prevent intra-abdominal adhesions.…”

“…[1][2][3] Postoperative intra-abdominal adhesion rates of 60-95% have been noted. [3] Postoperative adhesions can cause complications such as small bowel obstruction, chronic pelvic pain, and infertility that may affect an individual's quality of life.…”