The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus

Stewart, James E.; Wager, Karen A.; Friedlander, Arthur H.; Zadeh, Homayoun H.

doi:10.1034/j.1600-051x.2001.028004306.x

Cited by 246 publications

(262 citation statements)

References 23 publications

Supporting

Mentioning

232

Contrasting

Unclassified

Order By: Relevance

“…This result is in agreement with various other studies [51,52]. This result may be due to the fact that patients with well-controlled diabetes mellitus might respond to non-surgical therapy similarly well as healthy controls [48] and many of the patients in this study were controlled, diabetic patients.…”

Section: Latha Et Alsupporting

confidence: 82%

“…This is in agreement with a study by Grossi et al [49] and Kiran et al [52] who concluded that elimination of periodontal infection and improvement of periodontal inflammation significantly reduces the level of HbA1c in the short term, hence, improving diabetes metabolic control. Stewart et al [51] reported a reduction in HbA1c value from 9.5% to 7.6% 10 months following non-surgical therapy. A systematic review in 2010 concluded that periodontal therapy for type II diabetic patients is favorable and can reduce the HbA1c levels [53,54].…”

Section: Latha Et Almentioning

confidence: 99%

See 1 more Smart Citation

Effect of Non-Surgical Therapy on Salivary Nitric Oxide and Lipid Peroxidation Levels in Type Ii Diabetic and Non Diabetic Patients With Periodontal Disease

Latha

Uppoor

Nayak

et al. 2018

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: Reactive oxygen species have been identified as potential factors causing periodontal tissue destruction. Elevated levels of these in patients with chronic periodontitis and diabetes may aggravate the oxidative stress burden thereby accelerating the tissue damage associated with diabetes. The present study aimed to assess the effect of diabetes and periodontal disease on the oxidative stress markers and the effect of non-surgical therapy on these markers.Methods: A total of 50 participants were divided into four groups based on the selection criteria. In addition to clinical parameters and biochemical parameters (salivary nitric oxide [NO] and malondialdehyde [MDA] levels) were assessed using spectrophotometric method at baseline and 3 months after non-surgical periodontal therapy.Result: There was a statistically significant difference in the clinical parameters as well as NO and MDA levels in patients with type 2 diabetes and chronic periodontitis than other three groups at baseline and at 3 months after non-surgical periodontal therapy. Conclusion:Diabetes mellitus and periodontitis have a compounding effect on the oxidative stress. Periodontal therapy is essential for diabetic patients as it can lower the levels of oxidative damage.

show abstract

Section: Latha Et Alsupporting

confidence: 82%

Section: Latha Et Almentioning

confidence: 99%

Effect of Non-Surgical Therapy on Salivary Nitric Oxide and Lipid Peroxidation Levels in Type Ii Diabetic and Non Diabetic Patients With Periodontal Disease

Latha

Uppoor

Nayak

et al. 2018

Asian J Pharm Clin Res

View full text Add to dashboard Cite

show abstract

“…Local production of cytokines in the periodontal tissue affects glycemic control through systemic exposure and impairing intracellular insulin signaling thus potentially contributing to insulin resistance [23]. Hyperglycemic state may thus be enhanced in chronic periodontitis patients and periodontal therapy can therefore result in reduced HbA1c [24]. In this study, patients who received azithromycin showed comparatively higher reduction in HbA1c than patients who received metronidazole and SRP alone.…”

Section: Effect Of Oral Azithromycin and Metronidazole On Dental Paramentioning

confidence: 65%

Effect of Oral Azithromycin and Metronidazole as an Adjunct to Scaling and Root Planing on Glycemic Control in Type Ii Diabetic Patients With Chronic Periodontitis

Dhivya

Yogarajan²,

Shanmugarajan³

2017

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: Periodontitis, a chronic inflammatory disease characterized by destruction of the periodontal ligament and alveolar bone is the sixth complication of diabetes mellitus. Periodontal treatment that reduces gingival inflammation aids in the control of hyperglycemia. Therefore, the present study was designed to determine the effect of treating chronic periodontitis with oral antibiotics azithromycin and metronidazole on the level of serum glycated hemoglobin in type-II diabetic patients.Methods: This prospective observational study was carried out in the dental department of a tertiary care hospital for 9 months. Clinical and biochemistry reports of 90 patients were collected in designed case report forms. All statistical analyses were performed using IBM Statistical Package for Social Sciences 17 and Graph Pad Prism 7.0.Results: Significant reduction in all the clinical and dental parameters was comparatively higher in patients who received azithromycin than in patients who received metronidazole and scaling and root planning alone. Conclusion:Periodontal therapy with oral azithromycin can be employed as a supportive strategy for the management of diabetes mellitus. Henceforth, prevention and control of periodontal disease along with antibiotics must be considered an integral part of glycemic control. However, due to the lesser sample size in this study, further investigations are required to confirm the effect of periodontal therapy on systemic diseases.

show abstract

“…A number of interventional studies have shown that periodontal treatment may help in the improvement of metabolic control in type 2 diabetic patients [10,11,[16][17][18][19]. However, contradictory results have been demonstrated in other studies regarding the effects of periodontal therapy on glycaemic control [20][21][22].…”

Section: Non-surgical Periodontal Therapy (Srp)-effect On Glycaemic Cmentioning

confidence: 88%

The Effect of Scaling and Root Planing on Glycaemic Control, Periodontal Status and Gingival Crevicular f luid TN f - α Levels in an Indian Population- To Reveal the Ambivalent Link

K¹,

Suchetha

Puzhankara

et al. 2014

JCDR

View full text Add to dashboard Cite

The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus

Abstract: We interpret the data in the study to suggest that periodontal therapy was associated with improved glycemic control in persons with type 2 DM.

Cited by 246 publications

References 23 publications

Effect of Non-Surgical Therapy on Salivary Nitric Oxide and Lipid Peroxidation Levels in Type Ii Diabetic and Non Diabetic Patients With Periodontal Disease

Effect of Non-Surgical Therapy on Salivary Nitric Oxide and Lipid Peroxidation Levels in Type Ii Diabetic and Non Diabetic Patients With Periodontal Disease

Effect of Oral Azithromycin and Metronidazole as an Adjunct to Scaling and Root Planing on Glycemic Control in Type Ii Diabetic Patients With Chronic Periodontitis

The Effect of Scaling and Root Planing on Glycaemic Control, Periodontal Status and Gingival Crevicular f luid TN f - α Levels in an Indian Population- To Reveal the Ambivalent Link

Contact Info

Product

Resources

About