The Effect of Periodontal Treatment on Periodontal Bacteria on the Oral Mucous Membranes

Abstract

The aim of this study was to investigate the effect of conventional periodontal treatment on the prevalence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia on oral mucous membranes in patients with periodontitis. Fifteen patients were selected with moderate to severe periodontitis (mean age: 39.8 years, range: 26 to 58). From each patient the 4 deepest sites with bleeding on probing were selected for clinical and microbiological evaluation. At baseline, 6 weeks after oral hygiene instruction and extensive scaling and root planing, and 3 months after periodontal surgery, clinical parameters and microbiological samples including saliva, oral mucous membranes, and supra‐ and subgingival plaque were evaluated for the presence of the 3 test bacteria using indirect immunofluorescence. All clinical variables, except redness, showed a significant improvement after surgery. After treatment, the subgingival prevalence of the 3 putative periodontal pathogens had decreased significantly. However, almost no concomitant reduction in the prevalence of the bacteria was seen on the oral mucous membranes. This suggests that the oral mucous membranes may serve as a source for reinfection of the periodontium after treatment. J Periodontol 1996;67:478–485.

Intracellular Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in Buccal Epithelial Cells Collected from Human Subjects

“…It is not yet clear whether those two species are able to maintain themselves in the absence of a gingival crevice. Previous studies done by microbial culture have reported that A. actinomycetemcomitans and P. gingivalis disappear from the mouth when all teeth are removed (7,8). The negative results for the edentulous subject are interesting in that respect.…”

Cellular and humoral systemic and mucosal immune responses stimulated in volunteers by an oral polybacterial immunomodulator “Dentavax”

“…On the other side, the irrelevant host response adds to the pathogenesis of the disease. Accumulating data demonstrate that till now there is no unified strategy for the therapy of periodontal inflammations [3][4][5][6][7]. In spite of the numerous publications on the etiology and pathogenesis of periodontal infections, no common diagnostic markers characterizing the response to treatment exist [8,9].…”

Full-mouth treatment versus quadrant root surface debridement in the treatment of chronic periodontitis: a systematic review

“…12 Several studies have shown that the periodon topathogens can colonise other intraoral niches such as tongue dorsum, tonsils, saliva and other mucous membranes in addition to the periodontal pockets. 13,14 Intraoral translocation of periodon topathogens from one niche to another has been proven. 15,16 After root surface debridement, the subgingival microfl ora can re-establish from these niches.…”