The effect of pH on the structural evolution of accelerated biomimetic apatite

Chou, Yu-Fen; Chiou, Wen‐An; Xu, Yuhuan; Dunn, James C.Y.; Wu, Benjamin M.

doi:10.1016/j.biomaterials.2003.12.037

Cited by 149 publications

(151 citation statements)

References 20 publications

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“…A sharp small peak appeared at 3638cm -1 which accounts for OH -stretching vibration. Another relatively large band appeared at 3408cm -1 is also related to OH -stretching band [16][17][18][19][20][21].…”

Section: Precalcificationmentioning

confidence: 88%

“…Small peaks at 606 cm -1 and 562 cm -1 , assigned for PO 4 3-( 4 ) bending vibration, and around 474cm -1 indicate the growth of PO 4 3-( 2 ), which started to grow and become more differentiated, (Fig. 3), [16,18,19,21,22,25,26]. Therefore, the growth of a carbonated hydroxyapatite, where the carbonate groups have grown together with the phos- phate sites in the resultant phase, i.e., Type B, can be concluded [18].…”

Section: Biomimetic Coatingmentioning

confidence: 99%

“…3), [16,18,19,21,22,25,26]. Therefore, the growth of a carbonated hydroxyapatite, where the carbonate groups have grown together with the phos- phate sites in the resultant phase, i.e., Type B, can be concluded [18]. Nevertheless, the presence of the doublet of 873cm -1 and 962cm -1 indicate the presence of HPO 4 2-in the resultant coating [20,28].…”

Section: Biomimetic Coatingmentioning

confidence: 99%

“…Besides, a peak appeared at 710 cm -1 , is assigned to "in-plane" C-O bending vibration. Such peaks as a whole assure the presence of inorganic CO 3 2-group [18,19,22,24,25].…”

Section: Precalcificationmentioning

confidence: 99%

See 3 more Smart Citations

Biomimetic Coating of Precalcified Ti-6Al-4V Alloy

Adawy¹,

Abdel-Fattah²,

El-Sayed³

et al. 2009

TOMDJ

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Calcium hydroxyapatite, HA, (Ca 10 (PO 4 ) 6 (OH) 2 ) bioceramics, owing to their similarity with the human bone and dentin minerals, attract significant interest for orthopaedic and dental applications. Biological apatites, on the other hand, are carbonate substituted and calcium-deficient. Biomimetic coating of titanium and related alloys with carbonated apatitic calcium phosphate is an important area of research in implantology. While this paper specifically refers to coating Ti-6Al-4V, (TAV) the obtained results are valid with other related alloys as well.An attempt was made in the current research to accelerate the biomimetic coating process through precalcification of the alkali and heat treated alloy. The precalcification resulted in a homogenous layer of calcium precursors on the surface of the alloys. Such precursors accelerated the biomimetic deposition of carbonate hydroxyapatite (CHA) coat resembling that of the biomineral apatite upon soaking in Kukubo corrected simulated body fluid (1.5 c-SBF). The development of coats on Ti-6Al-4V surfaces were assessed by step by step diffuse reflectance infra-red spectroscopy and scanning electron microscopy.The essential information of biodeposition was obtained by following the uptake or release of calcium and inorganic phosphorus, Ca, iP, ionic species biochemically and mirrored by parallel electrical conductivity measurements of the soaking solutions.

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Section: Precalcificationmentioning

confidence: 88%

Section: Biomimetic Coatingmentioning

confidence: 99%

Section: Biomimetic Coatingmentioning

confidence: 99%

“…Besides, a peak appeared at 710 cm -1 , is assigned to "in-plane" C-O bending vibration. Such peaks as a whole assure the presence of inorganic CO 3 2-group [18,19,22,24,25].…”

Section: Precalcificationmentioning

confidence: 99%

See 2 more Smart Citations

Biomimetic Coating of Precalcified Ti-6Al-4V Alloy

Adawy¹,

Abdel-Fattah²,

El-Sayed³

et al. 2009

TOMDJ

View full text Add to dashboard Cite

show abstract

“…[1][2][3][4][5][6][7] Currently, this method is used to coat permanent implants [1][2][3][4] with the aim of improving biological compatibility and osteoconductivity, as well as degradable scaffolds that support skeletal tissue repair and regeneration. [5][6][7][8] Because direct bonding between an implant and bone can occur if a layer of bone-like mineral forms on the surface of the implant, 9 it has been hypothesized that the formation of such a mineral layer within the pores of a scaffold may enhance the conduction of host cells into the scaffold and also enhance the osteogenic differentiation of transplanted cells.…”

Section: Introductionmentioning

confidence: 99%

Ultrastructural analyses of nanoscale apatite biomimetically grown on organic template

et al. 2008

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The ultrastructure of nanoscale apatite biomimetically formed on an organic template from a supersaturated mineralizing solution was studied to examine the morphological and crystalline arrangement of mineral apatites. Needle-shaped apatite crystal plates with a size distribution of ~100 to ~1000 nm and the long axis parallel to the c axis ([002]) were randomly distributed in the mineral films. Between these randomly distributed needle-shaped apatite crystals, amorphous phases and apatite crystals (~20-40 nm) with the normal of the grains quasi-perpendicular to the c axis were observed. These observations suggest that the apatite film is an interwoven structure of amorphous phases and apatite crystals with various orientations. The mechanisms underlying the shape of the crystalline apatite plate and aggregated apatite nodules are discussed from an energy-barrier point of view. The plate or needle-shaped apatite is favored in single-crystalline form, whereas the granular nodules are favored in the polycrystalline apatite aggregate. The similarity in shape in both singlecrystalline needle-shaped apatite and polycrystalline granular apatite over a wide range of sizes is explained by the principle of similitude, in which the growth and shape are determined by the forces acting upon the surface area and the volume.

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Osteoporotic Bone Recovery by a Highly Bone‐Inductive Calcium Phosphate Polymer‐Induced Liquid‐Precursor

Yao

Lin

et al. 2019

Advanced Science

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Osteoporosis is an incurable chronic disease characterized by a lack of mineral mass in the bones. Here, the full recovery of osteoporotic bone is achieved by using a calcium phosphate polymer‐induced liquid‐precursor (CaP‐PILP). This free‐flowing CaP‐PILP material displays excellent bone inductivity and is able to readily penetrate into collagen fibrils and form intrafibrillar hydroxyapatite crystals oriented along the c‐axis. This ability is attributed to the microstructure of the material, which consists of homogeneously distributed ultrasmall (≈1 nm) amorphous calcium phosphate clusters. In vitro study shows the strong affinity of CaP‐PILP to osteoporotic bone, which can be uniformly distributed throughout the bone tissue to significantly increase the bone density. In vivo experiments show that the repaired bones exhibit satisfactory mechanical performance comparable with normal ones, following a promising treatment of osteoporosis by using CaP‐PILP. The discovery provides insight into the structure and property of biological nanocluster materials and their potential for hard tissue repair.

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The effect of pH on the structural evolution of accelerated biomimetic apatite

Cited by 149 publications

References 20 publications

Biomimetic Coating of Precalcified Ti-6Al-4V Alloy

Biomimetic Coating of Precalcified Ti-6Al-4V Alloy

Ultrastructural analyses of nanoscale apatite biomimetically grown on organic template

Osteoporotic Bone Recovery by a Highly Bone‐Inductive Calcium Phosphate Polymer‐Induced Liquid‐Precursor

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