Deformation of a hydrocarbon reservoir can ideally be used to estimate the effective stress acting on it. The effective stress in the subsurface is the difference between the stress due to the weight of the sediment and a fraction (effective stress coefficient) of the pore pressure. The effective stress coefficient is thus relevant for studying reservoir deformation and for evaluating 4D seismic for the correct pore pressure prediction. The static effective stress coefficient [Formula: see text] is estimated from mechanical tests and is highly relevant for effective stress prediction because it is directly related to mechanical strain in the elastic stress regime. The corresponding dynamic effective stress coefficient [Formula: see text] is easy to estimate from density and velocity of acoustic (elastic) waves. We studied [Formula: see text] and [Formula: see text] of chalk from the reservoir zone of the Valhall field, North Sea, and found that [Formula: see text] and [Formula: see text] vary with differential stress (overburden stress-pore pressure). For Valhall reservoir chalk with 40% porosity, [Formula: see text] ranges between 0.98 and 0.85 and decreases by 10% if the differential stress is increased by 25 MPa. In contrast, for chalk with 15% porosity from the same reservoir, [Formula: see text] ranges between 0.85 and 0.70 and decreases by 5% due to a similar increase in differential stress. Our data indicate that [Formula: see text] measured from sonic velocity data falls in the same range as for [Formula: see text], and that [Formula: see text] is always below unity. Stress-dependent behavior of [Formula: see text] is similar (decrease with increasing differential stress) to that of [Formula: see text] during elastic deformation caused by pore pressure buildup, for example, during waterflooding. By contrast, during the increase in differential stress, as in the case of pore pressure depletion due to production, [Formula: see text] increases with stress while [Formula: see text] decreases.