The Effect of Prior Carbohydrate Intake on the Oral Glucose Tolerance Test

Wilkerson, Hugh L. C.; Butler, Frank K.; Francis, John O's.

doi:10.2337/diab.9.5.386

Cited by 50 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The diet before the OGTT for patients with CGN and chronic diseases provided at least 300 g of carbohydrate and 70 g of protein with adequate amounts of calories ranging from 2000 kcal to 2086 kcal. 4 No patients examined by the OGTT in the present study were under prolonged physical inactivity or had signs of an infection. No menstruating women were included.…”

Section: Methodsmentioning

confidence: 96%

Abnormal Glucose Tolerance in Patients with Chronic Glomerulonephritis Without Renal Failure

et al. 1983

View full text Add to dashboard Cite

An oral glucose tolerance test and an assay of insulin receptor activity were performed in patients with chronic glomerulonephritis (CGN) to elucidate the aberration of glucose metabolism in such patients. Ninety of 123 patients with CGN without renal failure showed abnormal glucose tolerance, including 72.6% with IgA nephropathy, 81% with benign recurrent hematuria, 87% with chronic proliferative glomerulonephritis, 100% with membranoproliferative glomerulonephritis, and 80.0% with membranous nephropathy. Insulin responses in CGN patients during oral glucose tolerance tests showed lower levels of basal insulin and significantly higher levels after 90, 120, and 180 min compared with those of normal controls. The binding of radiolabeled insulin to blood mononuclear cells in 22 CGN patients with abnormal glucose tolerance was significantly (P = 0.0023) decreased in comparison with 5 normal controls. However, plasma obtained from such patients showed no significant (P = 0.4761) inhibition of the binding of insulin to normal mononuclear cells. It was concluded that glucose tolerance capacity was impaired in 80.4% of patients with CGN without renal failure. Such impairment of glucose metabolism might be due to decreased activity of insulin receptors on cells in CGN patients.

show abstract

Section: Methodsmentioning

confidence: 96%

Abnormal Glucose Tolerance in Patients with Chronic Glomerulonephritis Without Renal Failure

et al. 1983

View full text Add to dashboard Cite

show abstract

“…Recent considerations (1) indicate that negative findings may relate to low carbohydrate in the antecedent diet, or to effects of surgery or anesthesia, as well as to the supervention of hypoglycemia and resulting glycogenolysis. Our patients all had carbohydrate intakes above the minimum required to sustain normal glucose tolerance in nondiabetic humans (34) and were studied under conditions of minimal stress. Hypoglycemia developed in some, but not all of our studies in which insulin appeared to decrease the hepatic output of glucose-C14.…”

Section: Methodsmentioning

confidence: 99%

Conversion of Dl-Lactate-2-C14 or -3-C14 or Pyruvate-2-C14 to Blood Glucose in Humans: Effects of Diabetes, Insulin, Tolbutamide, and Glucose Load*

Meutter¹

1963

J. Clin. Invest.

View full text Add to dashboard Cite

“…Bran added to a diet reduced postprandial glucose and insulin areas or se rum lipids in subjects with impaired glucose tolerance [5]. Glucose tolerance was im paired after 5 days on a carbohydrate diet of 20 g/day in healthy subjects [6], Following 4 days on 150 g carbohydrates/day, normal glucose tolerance was restored in the same subjects. Recent studies propose that lowglycemic-index starchy foods have beneficial effects on glucose metabolism in healthy subjects [7] and in diabetic patients [8], Af ter 2 weeks on the diet, the subjects had a lower 12-hour glucose profile, and, in addi tion, the diet was less insulinogenic.…”

Section: Introductionmentioning

confidence: 88%

Plasma Glucose and Insulin, Urinary Catecholamine and Cortisol Responses to Test Breakfasts with High or Low Fibre Content: The Importance of the Previous Diet

Sundell¹,

Hallmans²,

Nilsson³

et al. 1989

Ann Nutr Metab

View full text Add to dashboard Cite

A 60-hour high-carbohydrate (high-CHO) diet or a 36-hour low-carbohydrate (low-CHO) diet was followed by 24 healthy women in a cross-over design to modify liver glycogen content. Thereafter each subject was given a high-sucrose breakfast, a high-protein, high-fibre breakfast or no breakfast. The two different breakfasts evoked larger plasma glucose responses following the low-CHO diet than when following the high-CHO diet. When the two breakfasts followed the same pre-period diet, no significant differences were observed. We conclude that the composition of the previous diet influences the postprandial response to meals and that a standardised diet shortly before test meal studies is of importance for the results in this type of studies.

show abstract

The Effect of Prior Carbohydrate Intake on the Oral Glucose Tolerance Test

Cited by 50 publications

References 0 publications

Abnormal Glucose Tolerance in Patients with Chronic Glomerulonephritis Without Renal Failure

Abnormal Glucose Tolerance in Patients with Chronic Glomerulonephritis Without Renal Failure

Conversion of Dl-Lactate-2-C14 or -3-C14 or Pyruvate-2-C14 to Blood Glucose in Humans: Effects of Diabetes, Insulin, Tolbutamide, and Glucose Load*

Plasma Glucose and Insulin, Urinary Catecholamine and Cortisol Responses to Test Breakfasts with High or Low Fibre Content: The Importance of the Previous Diet

Contact Info

Product

Resources

About