1950
DOI: 10.1097/00006534-195010000-00018
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The Effect of Priscoline, Papavetine, and Nicotinic Acid on Blood Flow in the Lower Extremity of Man

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Cited by 7 publications
(6 citation statements)
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“…Grayson's (29) statement, namely that a fixed relationship exists between the average value of blood flow in the tissue and local thermal conduction coefficient, i.e., that it is possible to measure absolute values of flow by means of a constant instrumental factor could be confirmed neither in later experiments by Linzell (50) in various organs, nor in our own experiments with artificially perfused sheep spleen (39). This stands in very good agreement with plethysmographic measurements (17,48,56). On the contrary, great local differences in the slope of the calibration curves were found.…”
supporting
confidence: 80%
“…Grayson's (29) statement, namely that a fixed relationship exists between the average value of blood flow in the tissue and local thermal conduction coefficient, i.e., that it is possible to measure absolute values of flow by means of a constant instrumental factor could be confirmed neither in later experiments by Linzell (50) in various organs, nor in our own experiments with artificially perfused sheep spleen (39). This stands in very good agreement with plethysmographic measurements (17,48,56). On the contrary, great local differences in the slope of the calibration curves were found.…”
supporting
confidence: 80%
“…A recent study in normal subjects wherein the effect of various drugs on the peripheral vessels was recorded by use of venous occlusion plethys-mography, skin temperatures and radioactive sodium uptake from the gastrocnemius muscle has shown that intravenous papaverine has a moderate vasodilating effect on the vessels in the skin and subcutaneous tissue in some individuals (14) . The drug was not as effective as priscoline as a vasodilator and less than 50%o of the subjects showed any significant vasodilatation.…”
Section: Resultsmentioning
confidence: 99%
“…The peripheral vascular effects of Priscoline have been studied by several investigators (1,2,3,4,5,6,7). It was shown, by means of skin temperature and plethysmographic studies, that this agent can increase total blood flow to the periphery.…”
Section: Introductionmentioning
confidence: 99%