The Effect of Probiotics on Immune System

Abstract

In recent years, the research into probiotics indicates that supplementing with probiotics is probably more important than taking a multi-vitamin or antibiotics. This paper presents the interaction between host-derived probiotics and immunomodulatory. Studies have revealed probiotics can produce a unique substance that affects the expression of particular genes which are related to immune regulation in humans. The effect of gastric microbiota such as Lactobacillus fermentum and Lactobacillus plantarum is an amazing example to demonstrate how they are able to regulate the immune system. In fact, the studies indicate that L. plantarum ZDY 2013 pretreatment can prevent gastric mucosal inflammation induced by H. pylori. In addition, L. fermentum UCO-979C-obtained from human gut shows an efficient growth in the rodent (Mongolian gerbil). It can stop stimulation to produce cytokines like IL8 by H. pylori in gastric adenocarcinoma human cells (AGS)cells.