The Effect of Radiological and Laboratory Parameters on Prognosis in COVID 19 Disease

Abstract

Objective: A previously unknown contagious disease, which later turned out to be a worldwide pandemic originated from Wuhan, capital of Hubei province in China by the end of 2019. While this upheaval affected numerous countries tragically, mortality rate and necessity for ICU were relatively low in Turkey. Methods: A total of 166 patients (65 at ICU, 101 at pandemic service) were analyzed to uncover effect of radiological and laboratory parameters on prognosis in COVID-19. One hundred and one patients (60.8%) were treated in pandemic service and 65 (39.15%) were treated in ICU. Results: Mean age of the patients in pandemic service was 61.1±16.2 (23−93) and of patients in ICU was 64.6±15.7 (15−90) (p>0.05). Initial mean CRP value for pandemic service group was 68.14±6.5 mg/dL (3.11−271), whereas it was 117.07±11.5 mg/dL (0−360) for ICU (p<0.05). Mean D-dimer value for the patients in ICU was 5572.2±1075.6 ng/mL and for the patients in pandemic service it was 1904.9±290.7 ng/mL (p<0.05). There was a correlation between CRP and D-dimer values (p<0.05). Of 66 patients in ICU group, 30(49.2%) had early stage CT findings, 22 (36.1%) had progressing stage CT findings and 9 (14.8%) had severe stage CT findings. However, of 101 patients in pandemic service group, 67 (66.9%) had early stage CT findings, 32 (31.7%) had progressing stage CT findings and 2 (2%) had severe stage CT findings. Conclusion: CT staging is a substantial prognostic factor and may help clinicians decide treatment modality. Furthermore, CRP and D-dimer values are also prognostic during follow-up. Thus, the necessity of taking these parameters into consideration while implementing treatment algorithms has emerged. As a conclusion, CT stage, CRP and D-Dimer values should be adopted as crucial prognostic factors in order to provide efficient healthcare.

Clinical and laboratory factors associated with hospitalization and mortality in the COVID-19 pandemic

“…In a study by Ozer et al with 166 patients, lung computed tomography involvement was found in 60.8% of COVID-19 patients hospitalized in the pandemic ward [25]. In this study, lung computed tomography involvement was detected in 59.4% of the patients followed up with the diagnosis of COVID-19 in the pandemic service, supporting the literature.…”

Is There a Relationship between Serum D-Dimer Levels and Thorax CT Severity Score in Patients with COVID-19?: A Retrospective Analysis

“…Thorax CT is frequently used in the diagnosis of COVID-19 pneumonia, in the course of the disease, in demonstrating progression and residual disease. The stages of radiological recovery in patients with COVID-19 pneumonia were reported by Akçay, et al [9]. In the initial phase (0-4 days), the main CT finding is ground glass density in the bilateral or In conclusion, we found that a high level of D-dimer in patients with COVID-19 was associated with thorax CT severity score.…”

Prediction of the Prognosis of Covid-19 Disease Using Deep Learning Methods and Boruta Feature Selection Algorithm

“…Hastalığın tespitinde ters transkripsiyon polimeraz zincir reaksiyonu (rt-PCR) testi, hastalığın erken evrelerinde veya düşük yüklü örneklerde yeterli duyarlılığa (% 60 -70) sahip olmasa da Covid-19'un tanısında kabul edilen standart referanstır (Fang et al, 2020). Öte yandan, yüksek duyarlılığı (% 98) nedeniyle bilgisayarlı tomografi (BT) görüntüleme ile de Covid-19'un akciğerdeki şiddeti ve seyri takip edilebilmektedir (Ai et al, 2020, Akbaş 2021, Ozer 2020, Cömert 2020. Bu nedenle Covid-19 hastalığının hızlı ve yüksek hassasiyette tespitinde, pulmoner evresinin radyologlar tarafından değerlendirilmesinde ve hastaların uygun triyajında BT görüntüleme çok önemli bir rol oynamaktadır.…”