The effect of rheological behaviour of a topical anaesthetic formulation on the release and permeation rates of the active compound

Effects of Carbopol^® 934 proportion on nanoemulsion gel for topical and transdermal drug delivery: a skin permeation study

“…37 In the deep skin layers (epidermis/dermis), drug deposition was highly significantly greater in NE and NG1 than in NG2 and NG3 (P,0.01). Similarly, Welin-Berger et al 38 reported that the drug release rates decreased as the formulations increased in viscosity. The results of this study suggest that NE and NG1 contained more nanosized droplets than NG2 and NG3 to react with the SC within a short time span.…”

Development of Abelmoschus esculentus (Okra)-Based Mucoadhesive Gel for Nasal Delivery of Rizatriptan Benzoate

“…Normally, drug release from hydrogel is governed by the diffusion. The apparent viscosity and polymeric chain complexity of the formulation influence diffusion of molecules [12].…”

Stability Studies of Nano-Scaled Emulsions Containing Ibuprofen for Topical Delivery.

“…The shear stress was applied in an increasing manner at a rate of 5 pascal/2 sec and the shear rate measurements were recorded. [11] The experiment was repeated for other samples and triplicate trials were done for each of them. Rheograms were drawn by plotting shear stress on the x axis and shear rate on the y axis.…”