The effect of shock waves on mineralization and regeneration of distraction zone in osteoporotic rabbits

Özkan, Enes; Şenel, Erman; Bereket, Mehmet Cihan; Önger, Mehmet Emin

doi:10.1080/07853890.2023.2192958

Cited by 3 publications

(1 citation statement)

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“…This therapy presents a novel avenue for both treatment and prevention of osteoporotic fractures. Recent studies using rabbit models of osteoporosis revealed that ESWT promotes www.jrsonweb.com osteoblast formation, reduces bone mass loss, increases bone trabeculae count, and elevates endogenous SMAD2 protein expression, suggesting ESWT's potential in promoting osteoblast maturation through the TGFb/SMAD2 pathway [25]. Moreover, a prospective randomized controlled trial on postmenopausal osteoporosis patients showed that concurrent use of alendronate sodium with varying energy flow densities of ESWT significantly improved hip bone mineral density, especially with higher energ y flow density (0.28 mJ/mm2) showing superior outcomes compared to lower energy flow density (0.15 mJ/mm2) [26].…”

Section: W H a T A R E T H E O P P O R T U N I T I E S A N D Challeng...mentioning

confidence: 99%

Shock Wave Medicine: A Transformative Evolution in Modern Medicine

Li,

Fan,

Sun

2023

jrs

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Since its inception as extracorporeal shock wave lithotripsy in the 1980s, the landscape of medical treatment has been revolutionized by the evolution of shock wave therapy. Over four decades, this therapy, now known as extracorporeal shock wave therapy (ESWT), has emerged as a cornerstone in modern medicine, redefining treatment paradigms across various medical disciplines. Certainly, despite the promising outcomes witnessed in various medical conditions such as musculoskeletal disorders, wound healing, urinary calculi, and erectile dysfunction, it is crucial to acknowledge that shock wave therapy’s relatively short clinical tenure necessitates a cautious approach. While its effectiveness has been repeatedly demonstrated, establishing industry-standard protocols through large-scale, prospective randomized controlled trials remains imperative to solidify its standing in medical practice. The integration of Artificial Intelligence technology holds significant promise for the future of shockwave medicine, enabling personalized treatment plans, real-time feedback, and improved cost-effectiveness. Keywords: Shock waves, ESWT, Shockwave

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Section: W H a T A R E T H E O P P O R T U N I T I E S A N D Challeng...mentioning

confidence: 99%