The effect of silymarin on the liver in thermal burn injury

Yemişen, Evren

doi:10.12991/mpj.2014186120

Cited by 3 publications

(2 citation statements)

References 45 publications

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“…Also, Yamisen et al . evaluated the positive effects of silymarin in burn-induced liver injury in burned rats and observed that both topical and systemic treatments with silymarin were effective in reversing this type of liver injury [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

The effect of silymarin on liver enzymes and antioxidant status in trauma patients in the intensive care unit: a randomized double blinded placebo-controlled clinical trial

Mirzaei¹,

Sabetian²,

Masjedi³

et al. 2021

ceh

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Section: Discussionmentioning

confidence: 99%

The effect of silymarin on liver enzymes and antioxidant status in trauma patients in the intensive care unit: a randomized double blinded placebo-controlled clinical trial

Mirzaei¹,

Sabetian²,

Masjedi³

et al. 2021

ceh

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“…It was also determined that both systemic and local administration of silymarin was effective against burn-induced oxidative damage and morphological alterations in rat skin (Toklu et al, 2006). Recently some researchers outlined that both local and systemic silymarin treatment was effective to reverse the effects of burn induced liver injury (Yemisen et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Comparison between the effect of silymarin and silver sulfadiazine on burned wound healing in rats

Aliabadi¹,

Valadaan²

2016

BJVM

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A burn is an injury caused by transfer of thermal energy into tissue resulting in disruption of its normal anatomical structure. An experiment was carried out to compare the effect of silymarin and silver sulfadiazine on burned wound healing in rat. In this study, 36 Wistar rats were divided into 6 groups. A burn was generated on the backs of all rats by brass probe. The burned areas in the first group (control) did not receive any medication, the second group received oral silymarin. Wound areas in third, fourth and fifth group were covered daily with 5%, 10% and 20% silymarin ointment. Silver sulfadiazine was applied as daily topical treatment of burned wound in the sixth group. At post injury days 0, 5, 7, 14 and 21, rats from each group were selected, sacrificed and burned skin tissue samples were collected for histopathological examination. Ulceration, acute inflammation, chronic inflammation, crust formation and granulation tissue formation were assessed. The result of this study showed that the use of 10% silymarin significantly enhanced the burn wound healing process as compared to silver sulfadiazine and other silymarin concentrations.

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Kinetics of Inflammatory Mediators in the Immune Response to Burn Injury: Systematic Review and Meta-Analysis of Animal Studies

Mulder,

Hooijmans,

Vlig

et al. 2024

Journal of Investigative Dermatology

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The effect of silymarin on the liver in thermal burn injury

Cited by 3 publications

References 45 publications

The effect of silymarin on liver enzymes and antioxidant status in trauma patients in the intensive care unit: a randomized double blinded placebo-controlled clinical trial

The effect of silymarin on liver enzymes and antioxidant status in trauma patients in the intensive care unit: a randomized double blinded placebo-controlled clinical trial

Comparison between the effect of silymarin and silver sulfadiazine on burned wound healing in rats

Kinetics of Inflammatory Mediators in the Immune Response to Burn Injury: Systematic Review and Meta-Analysis of Animal Studies

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