A novel micro-mesostructured SiO 2 /reduced graphene oxide (RGO) nanocomposite was successfully synthesized by means of simple one-step hydrothermal method under acidic conditions using tetraethoxysilane (TEOS) and graphene oxide (GO) as the raw material. The nanocomposites were characterized by TEM, XRD, FT-IR, TG-DSC, and N 2 adsorption-desorption. The results showed that GO was partially reduced to RGO without adding any reducing agent and SiO 2 nanoparticles (ca. 10 nm) were uniformly anchored on the surface of RGO. The optimized composite contained 75 wt.% SiO 2 and possessed hierarchical micro-mesoporous structure with surface area of 676 m 2 /g. The adsorption performance of synthesized SiO 2 /RGO samples was investigated by removal efficiency of Cr(VI) ions in wastewater. The Cr(VI) adsorption reached equilibrium in 30 min and 98.8% Cr(VI) adsorption efficiency was achieved at pH = 2 at 35 ∘ C. Stability tests showed that SiO 2 nanoparticles effectively prevented RGO from the restacking. The mechanisms of composite formation and for Cr(VI) adsorption were suggested.