The Effect of Soy Protein Beverages on Serum Cell Adhesion Molecule Concentrations in Prehypertensive/Stage 1 Hypertensive Individuals

Dettmer, Michelle; Alekel, D. Lee; Lasrado, Joanne A.; Messina, Mark; Carriquiry, Alicia; Heiberger, Kevin; Stewart, Jeanne W; Franke, Warren D.

doi:10.1080/07315724.2012.10720015

Cited by 7 publications

(2 citation statements)

References 139 publications

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“…These observations indicated that soybean protein supplementation could reduce E-selectin and leptin levels in plasma. However, intake of either cow’s milk or a soy protein beverage for eight weeks did not alter soluble cell AM concentrations in pre-hypertensive or stage 1 hypertensive individuals, suggesting that neither beverage diminished atherosclerotic CVD risk in mildly hypertensive individuals by improving circulating cell AM concentrations [ 140 ].…”

Section: Clinical Trialsmentioning

confidence: 99%

Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms

et al. 2017

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Epidemiological studies have shown that vegetable consumption is inversely related to the risk of cardiovascular diseases. Moreover, research has indicated that many vegetables like potatoes, soybeans, sesame, tomatoes, dioscorea, onions, celery, broccoli, lettuce and asparagus showed great potential in preventing and treating cardiovascular diseases, and vitamins, essential elements, dietary fibers, botanic proteins and phytochemicals were bioactive components. The cardioprotective effects of vegetables might involve antioxidation; anti-inflammation; anti-platelet; regulating blood pressure, blood glucose, and lipid profile; attenuating myocardial damage; and modulating relevant enzyme activities, gene expression, and signaling pathways as well as some other biomarkers associated to cardiovascular diseases. In addition, several vegetables and their bioactive components have been proven to protect against cardiovascular diseases in clinical trials. In this review, we analyze and summarize the effects of vegetables on cardiovascular diseases based on epidemiological studies, experimental research, and clinical trials, which are significant to the application of vegetables in prevention and treatment of cardiovascular diseases.

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Section: Clinical Trialsmentioning

confidence: 99%

Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms

et al. 2017

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“…Although some studies confirmed the beneficial effects of soy products on inflammation [20,24], some reports show the neutral effects of isoflavone supplements or isolated soy protein products [25,26]. However, those studies with soy milk or soy nut, which are the whole soy products and not just isoflavones or some components have usually significant positive effect on inflammation [27]. Rebholz et al showed that soy protein supplementation might reduce levels of E-selectin and leptin, but not any other inflammatory biomarkers including CRP, IL-6, and TNF-α [28].…”

Section: Variablesmentioning

confidence: 99%

Effects of a Low-Calorie, Low-Carbohydrate Soy Containing Diet on Systemic Inflammation Among Patients with Nonalcoholic Fatty Liver Disease: A Parallel Randomized Clinical Trial

et al. 2017

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Few studies have focused on the effects of a soy containing diet on inflammation and serum leptin level among patients with nonalcoholic fatty liver disease (NAFLD). Therefore, we aimed to determine the effects of such a diet in patients with NAFLD. Forty-five patients with NAFLD participated in this parallel randomized clinical trial for 8 weeks. Patients were randomly allocated to these 3 groups: 1) a low-calorie diet, 2) low-calorie low-carbohydrate diet, and 3) low-calorie low-carbohydrate soy containing diet. Low-calorie low-carbohydrate soy containing diet reduced fasting blood sugar (FBS) and serum insulin level significantly compared to other 2 groups (-11.6±2.8 vs. -6.3±1.7 and -3.1±1.0 mg/dl for FBS; and -5.1±1.2 vs. -1.2±0.3 and -1.7±0.5 mg/dl for serum insulin level). Serum hs-CRP level was also reduced significantly following low-calorie low-carbohydrate soy containing diet (-0.8±0.1 vs. -0.1±0.06 and -0.1±0.06 mg/dl). Both systolic and diastolic blood pressures were reduced significantly. Changes in leptin level tended to be different among 3 groups. After trial, 5 patients in each intervention group did not have NAFLD. From 6 patients in grade 2 at the beginning only 1 patient remained and others moved to grade 1. Low-calorie low-carbohydrate soy containing diet could reduce glycemic indices, hs CRP, systolic and diastolic blood pressure in a significant level in patients with NAFLD. However, these effects were dependent on baseline weight and further studies are needed to clarify the effect of such interventions in subjects with different BMI categories.

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Plant Protein, Animal Protein, and Cardiometabolic Health

Mariotti

2017

Vegetarian and Plant-Based Diets in Health and Disease Prevention

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The Effect of Soy Protein Beverages on Serum Cell Adhesion Molecule Concentrations in Prehypertensive/Stage 1 Hypertensive Individuals

Cited by 7 publications

References 139 publications

Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms

Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms

Effects of a Low-Calorie, Low-Carbohydrate Soy Containing Diet on Systemic Inflammation Among Patients with Nonalcoholic Fatty Liver Disease: A Parallel Randomized Clinical Trial

Plant Protein, Animal Protein, and Cardiometabolic Health

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