The Effect of Subepineural Platelet-rich Plasma on Regeneration of the Sciatic Nerve in a Rat Model

Abstract

HAND 11(1S) for CTS. We evaluated patients' decisional conflict regarding their decision for surgery. We also evaluated patients' knowledge about the disease and the perceived functional status as measured by the Disabilities of Arm, Shoulder and Hand (DASH) Questionnaire. Results: There was no difference in the Decisional Conflict Scale between both groups. Patients who viewed the decision aid had significantly better knowledge of CTS than those who did not. There was no correlation between the knowledge level and the Decisional Conflict Scale. However, higher DASH scores were correlated with lower decisional conflict. Conclusions: This study found that a decision aid does not reduce decisional conflict in patients with CTS, although it can help the patients be better informed. This study suggests that effective doctor-patient communication continues to be the most important way to reduce the decisional conflict in patients with CTS, and should be more emphasized for patients with less severe symptoms, as they have greater decisional conflict than those with severe symptoms.

An Overview of Platelet Products (PRP, PRGF, PRF, etc.) in the Iranian Studies

“…In 2015, a silicon tube filled with PRP [ 73 ], and in 2016 PRP injection under the perineurium proximal and distal to a cut in the sciatic nerve [ 74 ] were compared with a control group (only normal saline) in animals. There was no significant difference in the number of axons.…”

“…The two studies in this area were performed in 2015 [ 73 ] and 2016 [ 74 ], aiming to repair the sciatic nerve after cutting it in animal models. This has enjoyed better effects regarding the amount of myelin concentration.…”

Comparison of melatonin and curcumin effect at the light and dark periods on regeneration of sciatic nerve crush injury in rats

“…As a result, many people suffer these injuries every year. These injuries cause a number of problems including severe disability, reduced QOL and immense costs (Fatemi et al, 2016[10]; Jones et al, 2016[14]). The etiological identification of the affected lesions is highly diverse (it can include elongation, section, laceration, crushing) (Caillaud et al, 2018[4]).…”