2021
DOI: 10.1038/s41598-021-81814-3
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The effect of the definition of ‘pandemic’ on quantitative assessments of infectious disease outbreak risk

Abstract: In the early stages of an outbreak, the term ‘pandemic’ can be used to communicate about infectious disease risk, particularly by those who wish to encourage a large-scale public health response. However, the term lacks a widely accepted quantitative definition. We show that, under alternate quantitative definitions of ‘pandemic’, an epidemiological metapopulation model produces different estimates of the probability of a pandemic. Critically, we show that using different definitions alters the projected effec… Show more

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Cited by 29 publications
(14 citation statements)
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“…There is no unambiguous strict definition of an epidemic wave or a specific threshold of cases that marks the beginning of a new wave or just a phase of the previous one in recurrences [ 17 ]. Even if operational definitions have been proposed, pandemic waves should not be simplified as incidence curves [ 18 ] since other indicators are needed to interpret and create prediction models, considering under-ascertainment and indicators’ limits [ 19 ].…”
Section: Resultsmentioning
confidence: 99%
“…There is no unambiguous strict definition of an epidemic wave or a specific threshold of cases that marks the beginning of a new wave or just a phase of the previous one in recurrences [ 17 ]. Even if operational definitions have been proposed, pandemic waves should not be simplified as incidence curves [ 18 ] since other indicators are needed to interpret and create prediction models, considering under-ascertainment and indicators’ limits [ 19 ].…”
Section: Resultsmentioning
confidence: 99%
“…Our model adopted a star network topology [28,29] to represent the contacts between the first generation and the susceptible employees. The central hub of the network represents the firstgeneration cases who arrive at the workplace.…”
Section: Network Structurementioning
confidence: 99%
“…An epidemic is typically more localized, affecting only a particular country or region, whereas a pandemic has a global impact Dicker, et al [11] and Kelly [12]. Nevertheless, this classical description of a pandemic ignores the severity of the spreading disease or societal immunity, so there is no consensus on what constitutes a pandemic, and different schools of thought exist based on these limitations [12,13]. Some argue that the name should be based on the severity of the disease and the number of deaths, while others believe it should be based on its spread rate.…”
Section: Epidemiological Disastersmentioning
confidence: 99%