The effect of the dentifrice on gingivitis and dental plaque: A 6-week clinical study in India

Prasad, K. V. V.; Anupama, I; Rao, Nagabhushan Koratagere Hanumanta; Sreenivasan, Prem K.; Subramanyam, Ravi; Kulkarni, Raghavendra

doi:10.4103/2319-5932.153548

Cited by 2 publications

(14 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the exception of two studies, all reported to be randomized. Only two studies had a parallel design . The others all used a crossover design.…”

Section: Resultsmentioning

confidence: 99%

“…All the studies included evaluated overnight plaque scores in the morning before brushing. In one study, the period of no oral hygiene extended to 12 hours and, in two other studies, to 24 hours . A fourth study used a power brush …”

Section: Resultsmentioning

confidence: 99%

“…The studies were carried out in several countries around the world, which included India, China, the UK and the United States …”

Section: Resultsmentioning

confidence: 99%

“…A total of 456 participants provided data for this review. Participants ranged from experienced employee dentifrice panels to non‐dental populations …”

Section: Resultsmentioning

confidence: 99%

“…In the studies, there were several dropouts. Two participants did not complete the study protocol, and 15 participants were ineligible due to migration, unforeseen health events and other unspecified reasons . One study did not describe dropouts…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

What is the effect of active ingredients in dentifrice on inhibiting the regrowth of overnight plaque? A systematic review

Valkenburg

Slot

Weijden

2019

Int J Dental Hygiene

View full text Add to dashboard Cite

Objectives:The aim of this systematic review was to establish the adjuvant clinical effect of brushing with a dentifrice containing purported active ingredients as compared to a regular sodium fluoride dentifrice with respect to the inhibition of overnight dental plaque regrowth from studies with human participants.Methods: MEDLINE-PubMed, EMBASE and Cochrane CENTRAL were searched, up to June 2019. The inclusion criteria were controlled clinical trials with participants aged ≥ 18 years in good general health. Studies were included that evaluated the effect of toothbrushing with a dentifrice on the inhibition of overnight dental plaque regrowth when an active ingredient was added to the dentifrice as compared to a common sodium fluoride product. Data were extracted from the eligible studies, the risk of bias was assessed, and a meta-analysis was performed where feasible.Result: Independent screening of 213 unique papers resulted in 10 eligible publications that provided 14 comparisons. Stannous fluoride and triclosan dentifrices were found as the active ingredients. The descriptive analysis indicated that all, but two comparisons demonstrated an additional effect on the active-ingredient dentifrice.The meta-analysis supported and strengthened these findings. It showed that when plaque was scored digitally, a DiffM was −3.15(95% CI [−4.61:-1.69], P < .001, prediction interval [−5.07;-1.24]). When plaque was scored clinically, the difference of means (DiffM) was −0.33(95% CI [−0.49:-0.16], P < .001, prediction interval [−0.87; 0.21]). Conclusion:The results of this review demonstrate moderate-quality evidence that brushing with an active-ingredient dentifrice with stannous fluoride or triclosan does provide an added clinically relevant effect concerning plaque inhibition capabilities that surpass the effect of a regular sodium fluoride dentifrice. K E Y W O R D S dentifrice, oral hygiene, plaque, plaque inhibition, plaque regrowth, systematic review, toothbrushing, toothpaste | 129 VALKENBURG Et AL. S U PP O RTI N G I N FO R M ATI O N Additional supporting information may be found online in the Supporting Information section. How to cite this article: Valkenburg C, Else Slot D, Van der Weijden GA. What is the effect of active ingredients in dentifrice on inhibiting the regrowth of overnight plaque? A systematic review. Int J Dent Hygiene. 2020;18:128-141.

show abstract

“…With the exception of two studies, all reported to be randomized. Only two studies had a parallel design . The others all used a crossover design.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…The studies were carried out in several countries around the world, which included India, China, the UK and the United States …”

Section: Resultsmentioning

confidence: 99%

“…A total of 456 participants provided data for this review. Participants ranged from experienced employee dentifrice panels to non‐dental populations …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

What is the effect of active ingredients in dentifrice on inhibiting the regrowth of overnight plaque? A systematic review

Valkenburg

Slot

Weijden

2019

Int J Dental Hygiene

View full text Add to dashboard Cite

show abstract

Identification and Antimicrobial Susceptibility Testing of Pathogenic Micro-Organism From Dental Patients

Sakthivel

Pm²,

D³

2016

Asian J Pharm Clin Res

View full text Add to dashboard Cite

ABSTRACT Objective: To isolate and identify aerobic microbes present in the periodontal infected patients and to evaluate the choice of antibiotics in the management of periodontal diseases. Methods: In this study, these patients have not been treated previously for their conditions. An informed consent was obtained from these patients before collection of an oral swab. This study was approved by the Institutional Ethical Committee. The details of the patient’s age, sex, and clinical details were recorded on a per forma meant for this study. The following methodologies were adopted for the isolation and identification of the microorganisms from these cases. Results: In this study out of 50 oral samples, culture positivity was recorded in 43 (86%) cases and no growth in 7 (14%) cases. Antibiotic susceptibility test using to identified as resistant, sensitive, intermediate of pathogenicity of oral microbes. Such antibiotics were methicillin, ceftazidime, clindamycin, amikacin, cloxacillin, and cefotaxime. This study should be kept in mind when a local application of antibacterial compounds is used in the therapy of periodontal disease. Conclusion: This study highlights the different organisms involved in the different types of dental infections. The antibiotic pattern shown in this work will be a guide to the clinician in the selection of proper antibiotics for the treatment of these infections. Hence in this study, the limitations were time and the number of patients. For better outcomes, a larger study population for a longer period of time should be undertaken to know the bacteriology and to the select the effective drugs of choice for dental infections. A comparative study of bacteriology and mycology and its antimicrobial property would be very fruitful in the future. Keywords: Dental, Periodontal, Bacteria, Antibiotics.

show abstract

The effect of the dentifrice on gingivitis and dental plaque: A 6-week clinical study in India

Cited by 2 publications

References 13 publications

What is the effect of active ingredients in dentifrice on inhibiting the regrowth of overnight plaque? A systematic review

What is the effect of active ingredients in dentifrice on inhibiting the regrowth of overnight plaque? A systematic review

Identification and Antimicrobial Susceptibility Testing of Pathogenic Micro-Organism From Dental Patients

Contact Info

Product

Resources

About