The effect of the natural raw barite and the dolomite material on borate glass formation

Abdellaoui, K.; Ratep, A.; Boumaza, A.; Kashif, I.; Donya, Hossam

doi:10.4314/jfas.v10i1.21

Cited by 12 publications

(4 citation statements)

References 34 publications

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“…Fourier analysis of the formed BG nanofibers revealed different bands at 3,450, 2,278, 1,627, 1,411, 1,072, and 468.72 ( Figure 3G ). The bands corresponding to (OH) stretching groups are shown at peaks 3,450 and 1,627 ( Jabeen and Rafique, 2014 ; Abdellaoui et al, 2018 ). While the band at 2,278 indicated the presence of (Ca (CO 3 ) 2 ) bond in the formed nanofibers ( Abdellaoui et al, 2018 ).…”

Section: Resultsmentioning

confidence: 99%

“…The bands corresponding to (OH) stretching groups are shown at peaks 3,450 and 1,627 ( Jabeen and Rafique, 2014 ; Abdellaoui et al, 2018 ). While the band at 2,278 indicated the presence of (Ca (CO 3 ) 2 ) bond in the formed nanofibers ( Abdellaoui et al, 2018 ). Moreover, the peak at 1,411 is assigned to the (BO 3/2 ) bond according to ( Abdellaoui et al, 2018 ) and ( Shao et al, 2015 ).…”

Section: Resultsmentioning

confidence: 99%

“…While the band at 2,278 indicated the presence of (Ca (CO 3 ) 2 ) bond in the formed nanofibers ( Abdellaoui et al, 2018 ). Moreover, the peak at 1,411 is assigned to the (BO 3/2 ) bond according to ( Abdellaoui et al, 2018 ) and ( Shao et al, 2015 ). On the other hand, the band at 1,072 can be assigned for asymmetric (Si-O-Si) bond along with borate in the BO 4 group ( Shao et al, 2015 ; Abdellaoui et al, 2018 ).…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, the peak at 1,411 is assigned to the (BO 3/2 ) bond according to ( Abdellaoui et al, 2018 ) and ( Shao et al, 2015 ). On the other hand, the band at 1,072 can be assigned for asymmetric (Si-O-Si) bond along with borate in the BO 4 group ( Shao et al, 2015 ; Abdellaoui et al, 2018 ). Furthermore, the chemical analysis revealed a (Si-O-Si) bond at band 468.72 ( Jabeen and Rafique, 2014 ).…”

Section: Resultsmentioning

confidence: 99%

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Nanoscale borosilicate bioactive glass for regenerative therapy of full-thickness skin defects in rabbit animal model

Elshazly

Saad

Backly

et al. 2023

Front. Bioeng. Biotechnol.

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Bioactive glass (BG) occupies a significant position in the field of hard and soft tissue regeneration. Different processing techniques and formulas have been introduced to expand their regenerative, angiogenic, and antibacterial properties. In the present study, a new formula of bborosilicate bioactive glass nanofibers was prepared and tested for its wound-healing efficacy in a rabbit animal model. The glass formula ((1–2) mol% of B2O3 (68–69) mol% of SiO2, and (29–30) mol% of CaO) was prepared primarily by the sol-gel technique followed by the electrospinning technique. The material was characterized for its ultrastructure using scanning electron microscopy, chemical composition using FTIR, and its dynamic in vitro biodegradability using ICP-AES. Twelve rabbits were subjected to surgical induction of full-thickness skin defects using a 1 cm2 custom-made stainlessteel skin punch. The bioactive glass nanofibers were used as a grafting material in 6 experimental rabbits, while the defects in the remaining rabbits were considered as the negative control samples. All defects were assessed clinically for the decrease in wound size and clinical signs of healing and histologically for angiogenesis, collagen density, inflammatory response, cell recruitment, epithelial lining, and appendages at 1,2 and 3 weeks following the intervention. Structural analysis of the glass fibers confirmed their nano-size which ranged from 150 to 700 nm. Moreover, the chemical analysis confirmed the presence of SiO2 and B2O3 groups within the structure of the nanofibers. Additionally, dynamic biodegradation analysis confirmed the rapid degradation of the material starting from the first 24 h and rapid leaching of calcium, silicon, and boron ions confirming its bioactivity. The wound healing study of the nanofibrous scaffold confirmed its ability to accelerate wound healing and the closure rate in healthy rabbits. Histological analysis of the defects confirmed the angiogenic, regenerative and antibacterial ability of the material throughout the study period. The results unveil the powerful therapeutic properties of the formed nanofibers and open a new gate for more experimental and clinical applications.

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Section: Resultsmentioning

confidence: 99%