The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise

Kocot, Krzysztof

doi:10.13075/ijomeh.1896.01533

Cited by 4 publications

(5 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, air pollution, especially particulate matter, induces nitrogen oxide production by pulmonary epithelial cells [36]. Several studies reported FeNO increasing after exposure to air pollution during exercise in healthy adults [16,37] and positive correlations between outdoor air pollutant levels and post-exercise changes in FeNO [38]. These effects were not observed in a study which assessed the impact of exposure to low levels of air pollution (PM 2.5 : 2-17 µg/m 3 ) [25].…”

Section: Discussionmentioning

confidence: 99%

Acute FeNO and Blood Pressure Responses to Air Pollution Exposure in Young Adults during Physical Activity

Kocot

Barański

Melaniuk-Wolny

et al. 2020

IJERPH

Self Cite

View full text Add to dashboard Cite

During physical exercise, the absorbed dose of air pollutants increases. Acute effects of exposure to air pollutants during exercise in healthy young adults remain poorly documented. The aim of this study was to assess the acute responses in fractionated exhaled nitric oxide (FeNO) and blood pressure to air pollution exposure during exercise in young adults with different physical activity levels (low or high). In this study, 76 healthy university students participating in physical activity classes (low level of physical activity) and attending sports training (high level of physical activity) completed two indoor exercise trials when air pollutant concentrations were high (exposure trial) and when the quality of the air was good (control trial). We monitored indoor particulate matter with diameter <10 µm and <2.5 µm (PM10 and PM2.5) and outdoor PM10, nitric oxides (NO2, NOx, NO), and sulfur dioxide (SO2) concentrations. Systolic and diastolic blood pressure (SBP and DBP), heart rate (HR), oxygen saturation (SpO2), and FeNO were measured at baseline and after 45–60 min of physical activity. There were no significant differences between physiological responses to training performed under different exposure conditions in blood pressure, HR, and SpO2. Significant positive correlations between post-exercise ΔFeNO during exposure trials and ambient air pollutants were found. FeNO increase during the exposure trial was associated with a higher physical activity level and higher outdoor PM10 and NO2 concentrations. In young and healthy adults, some differences in physiological responses to physical activity between polluted and control environments could be observed. Participants with a high physical activity level were more likely to have an increase in FeNO after exercise in a polluted environment but not after the control exercise trials.

show abstract

Section: Discussionmentioning

confidence: 99%

Acute FeNO and Blood Pressure Responses to Air Pollution Exposure in Young Adults during Physical Activity

Kocot

Barański

Melaniuk-Wolny

et al. 2020

IJERPH

Self Cite

View full text Add to dashboard Cite

show abstract

“…Nevertheless, only a few research addressed the impact of allergy on the respiratory responses to air pollution exposure during exercise. The author's previous study showed different responses in terms of FeNO in young males with and without upper-respiratory allergy doing short intensive exercise on a cycle ergometer [31]. Only in subjects without allergy did post-exercise changes in FeNO correlate with air pollutants concentrations recorded during exercise.…”

Section: Discussionmentioning

confidence: 98%

Exercise under Exposure to Air Pollution and Spirometry in Healthy Adults with and without Allergy

et al. 2021

Self Cite

View full text Add to dashboard Cite

Ambient air pollution is a major environmental threat to human health. The acute effects of exposure to ambient air pollution during physical exercise may depend on allergy status. The aim of the study was to assess the acute respiratory responses to air pollution exposure during physical training in young adults with and without allergies. The studied group included 71 healthy young adults (n = 16 with allergy and n = 55 without allergy). Students completed two indoor physical training trials lasting 45–60 min: when air pollutants concentrations were high (exposure trial) and low (control trial). During each trial, we monitored outdoor and indoor environmental conditions. Participants performed spirometry at baseline and directly after the exercise. Exercise during exposure trials led to a small decrease in the percentage of predicted forced expiratory volume in 1 s (FEV1 ref). Only during the control trials did the FEV1/forced vital capacity quotient (FEV1/FVC) statistically significantly increase. Moreover, just in the allergy group, there were statistically significant negative correlations between post-exercise FEV1/FVC change and 3 h average outdoor particulate matter with aerodynamic diameter <10 µm (PM10) and nitrogen dioxide (NO2) concentrations (PM10: r = −0.54, p = 0.02, NO2: r = −0.60, p = 0.02). In young and healthy adults, sports training under exposure to high levels of ambient air pollutants leads to a small decrease in FEV1. The allergy might be a modifying factor in the respiratory responses to air pollution. Post-exercise decrease in FEV1/FVC was related to pre-exercise 3 h averages of PM10 and NO2 only in people with ever-diagnosed upper-respiratory allergy.

show abstract

“…Therefore, they concluded that the long-term benefits of physical activity in preventing the development of asthma and COPD in healthy elderly subjects can outweigh the risks associated with increased exposure to air pollution, including during physical activity, in addition to potentially allowing effective control of the disease in patients with COPD [70]. In this same sense, in a study that investigated the effects of physical exercise in the context of exposure to PM 2.5 for men with and without allergic conditions, it was concluded that exposure to air pollution during short-term and moderate-intensity exercise did not have an acute negative impact on respiratory and cardiovascular function in healthy young men [71].…”

Section: Discussionmentioning

confidence: 98%

Modulation of the Cardiovascular Effects of Polycyclic Aromatic Hydrocarbons: Physical Exercise as a Protective Strategy

Rojas,

Saavedra,

Morales

et al. 2023

Toxics

View full text Add to dashboard Cite

Exposure to polycyclic aromatic hydrocarbons (PAHs) present in air pollution increases cardiovascular risk. On the contrary, physical exercise is a widely used therapeutic approach to mitigate cardiovascular risk, but its efficacy in an environment of air pollution, particularly with PAHs, remains unclear. This study investigates the effects of exercise on inflammation, endothelial dysfunction, and REDOX imbalance due to PAH exposure using a mouse model. Twenty male BALB/c mice were subjected to a mixture of PAHs (phenanthrene, fluoranthene, pyrene) in conjunction with aerobic exercise. The investigation evaluated serum levels of inflammatory cytokines, gene expression linked to inflammatory markers, endothelial dysfunction, and REDOX imbalance in aortic tissues. Furthermore, the study evaluated the expression of the ICAM-1 and VCAM-1 proteins. Exercise led to notable changes in serum inflammatory cytokines, as well as the modulation of genes associated with endothelial dysfunction and REDOX imbalance in aortic tissue. In turn, exercise produced a modulation in the protein expression of ICAM-1 and VCAM-1. The findings implicate the potential of exercise to counter PAH-induced damage, as demonstrated by changes in markers. In conclusion, exercise could mitigate the adverse effects related to exposure to PAHs present in air pollution, as evidenced by changes in inflammatory markers, endothelial dysfunction, and REDOX imbalance.

show abstract

The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise

Cited by 4 publications

References 21 publications

Acute FeNO and Blood Pressure Responses to Air Pollution Exposure in Young Adults during Physical Activity

Acute FeNO and Blood Pressure Responses to Air Pollution Exposure in Young Adults during Physical Activity

Exercise under Exposure to Air Pollution and Spirometry in Healthy Adults with and without Allergy

Modulation of the Cardiovascular Effects of Polycyclic Aromatic Hydrocarbons: Physical Exercise as a Protective Strategy

Contact Info

Product

Resources

About