The increase in average life expectancy, accompanied by medical and technological advances, translates into an increase in chronic diseases and a constant updating of therapeutic strategies whose success depends on patient compliance. This scoping review followed the JBI methodology, according to the PCC method, and the aim was to identify measures associated with nursing care that improve the therapeutic adherence of the elderly with a chronic disease. These nursing interventions include continuous monitoring and surveillance, in person or digitally, using videos, remote monitoring software, or teleconsultations; personalized therapeutic plans; skills training based on a model of information, motivation, and behavior; the explanation of the value and therapeutic intent of the care plan; cognitive behavioral therapy; and the continuous validation through the teach-back method. Evidence shows the relevance of nursing intervention in the process of health education to the elderly person.