The effectiveness of acupoint herbal patching for constipation after stroke

Abstract

Background:Constipation is one of the common problems in stroke patients, which seriously affects the life quality of patients and even leads to the recurrence of cerebrovascular disease. The clinical trials of acupoint herbal patching (AHP) in the adjuvant treatment of constipation after stroke (CAS) is currently in progress. However, there is no systematic review or meta-analysis to evaluate the effects of AHP on CAS.Methods:We will search articles in 8 electronic databases including the Cochrane Central Register of Controlled Trials, PubMed, Embase, the Web of Science, China National Knowledge Infrastructure, the Chinese Biomedical Literature Database, Wanfang Database, and the Chinese Scientific Journal Database for randomized controlled trials of CAS treated by AHP from their inception to November 1, 2021. The primary outcome measures will be clinical effective rate, defecation frequency, improvement of clinical symptoms including complete spontaneous bowel movements. The data meeting the inclusion criteria were analyzed by RevMan V.5.4 software. Two authors evaluated the study using the Cochrane collaborative risk bias tool. We will use a scoring method to assess the overall quality of evidence supporting the main results.Results:This study will analyze the clinical effective rate, defecation frequency, improvement of clinical symptoms including complete spontaneous bowel movements after stroke.Conclusion:The findings of this systematic review will provide evidence to evaluate the effectiveness and safety of AHP for CAS.INPLASY registration number:INPLASY202210065.

Study on the effect of acupunture treatment on autonomic nerve dysfunction in convalescent period of stroke based on heart rate variability assessment technique

“…Studies have revealed that acupuncture has a bidirectional adjustment to the heart rate of healthy people, which is equivalent to the impact of acupuncture on balancing yin and yang, [21] and the vagus nerve is the key reaction. [22,23] Modern studies [23][24][25][26] have found that Neiguan is close to the median nerve and overlaps with the innervated nerve segments of the heart, and the information of acupuncture at Neiguan can reach the cardiovascular center, namely the nucleus of the solitary tract, the posterior hypothalamus and the preoptic area-the front part of the hypothalamus. In the early stage of our research group, a patient with mild autonomic dysfunction in the convalescence period of stroke and a severe patient were acupunctured with bilateral Zusanli and bilateral Neiguan, respectively, and we found that the HRV values of the 2 patients reached equilibrium at 20 minutes and 25 minutes of acupuncture.…”

Efficacy and safety of blood-activating herbs combined with edaravone in the treatment of acute ischemic stroke: A protocol for systematic review and meta-analysis

“…The quality of evidence regarding patient outcomes will be assessed by the Grading of Recommendations Assessment, Development, and Evaluation methodology (GREAD). [13] The results of the quality of evidence assessment will be categorized into 4 grades: high, medium, low, and very low.…”