The effectiveness of manual therapy for relieving pain, stiffness and dysfunction in knee osteoarthritis: A systematic review and meta-analysis

Abstract

, and at 12 months Group 1A had on average lower calorie intake than the groups 2A (-781.8, CI-1472.7,-91.0, p¼0.008) and 3A (-885.8, CI-1599.3,-172.2, p ¼ 0.001). There was no correlation between calories intake and waist-hip ratio at baseline and reassessment with any of the questionnaires. BMI and percentage of body fat correlated with WOMAC, WOMAC pain, VAS and Lequesne scores at baseline and at reassessment. Only changes in BMI correlated weakly with one-year results of the WOMAC (r¼-0.172, p¼0.016), WOMAC pain (r¼-0.193, p¼0.007), LEQUESNE (r¼-0.197, p¼0.006) and SF-36-MCS (r¼0.160, p¼0.027); and with changes in WOMAC (r¼0.220, p¼0.002), WOMAC pain (r¼0.199, p¼0.006), VAS (r¼0.170, p¼0.018). Changes in porcentage of body fat did not correlate with any of the pain, function and quality of life changes. Conclusions: The multi-professional treatment improved percentage of body fat at one year. This improvement does not correlate with classes, telephone calls or improvements in pain, function and quality of life questionnaires (WOMAC, WOMAC pain, VAS, LEQUESNE and SF-36). Calorie intake improved and was influenced by telephone calls and classes one month apart, and does not correlate with changes in pain, function and quality of life. Changes in BMI correlated with changes in pain and function but not with quality of life.

Evaluation of comprehensive ambulatory rehabilitation of people over 60 years of age

“…The results of the meta-analysis of Xu et al indicate that manual therapy significantly contributed to alleviation of pain, minimized stiffness and improved functional capacity of patients diagnosed with osteoarthritis of knee joint [19]. On the other hand, in the population of seniors suffering from pain in the cervical spine, it was proven that a cycle of physiotherapy significantly reduced the frequency of their occurrence [20].…”

Associations between serum S100A8/S100A9 and knee symptoms, joint structures and cartilage enzymes in patients with knee osteoarthritis

“…The most common symptoms of knee OA are pain, stiffness, and physical dysfunction, which affect the quality of life of OA patients 26 . The WOMAC is the most commonly used disease-specific measure of outcome used in OA, and has 24 items with a total score and three subscales: pain, stiffness and physical function 27 .…”

Medical rehabilitation in the combination treatment of rheumatic diseases: a review

“…Так, Q. Xu и соавт. [94] оценили действие этого метода по материалам 14 РКИ (n=841). Согласно полученным данным, мануальная терапия эффективно уменьшала боль (РСЗ -0,61; 95% ДИ от -0,95 до -0,28), скованность (РСЗ -0,58; 95% ДИ от -0,95 до -0,21), улучшала функцию (РСЗ -0,49; 95% ДИ от -0,76 до -0,22) и общий счет (РСЗ -0,56; 95% ДИ от -0,78 до -0,35) по WOMAC.…”