The effectiveness of self‐performed mechanical plaque control with triclosan containing dentifrices

Hioe, K.P.K.J.; Weijden, G.A. van der

doi:10.1111/j.1601-5037.2005.00150.x

Cited by 56 publications

(61 citation statements)

References 35 publications

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“…It has a broad spectrum of antibacterial activity and a significant anti-plaque effect, without staining the teeth. Systematic reviews of six-month clinical studies have concluded that formulations containing triclosan and copolymer significantly improve plaque control and periodontal health (15)(16)(17). Toothpastes containing triclosan and zinc citrate are also effective in improving plaque control and gingival health (18)(19)(20)(21).…”

Section: E978mentioning

confidence: 99%

Dentifrices; an update

Davies¹,

Scully²,

Preston³

2010

Med Oral

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Objectives; The objective of this paper was to review the published evidence concerning the efficacy and potential for adverse reactions of modern dentifrices toothpastes. Data sources; Publications cited on MEDLINE since 1990. Some further pre-1990 publications are also referenced. Data selection; Studies concerning the efficacy of dentifrices and their components and any related putative adverse incidents. Data extraction; Papers were scrutinised for scientific and trial data. Data synthesis; Data concerning the efficacy of dentifrice components were summarised. Conclusions; The efficacy of fluoride salts in dentifrices in reducing dental caries is well established. Toothpastes, containing triclosan, are effective in improving plaque control, gingivitis and periodontal health. Other toothpaste formulations are effective in reducing the formation of calculus, extrinsic tooth stain, dentine sensitivity and oral malodour. The consumer now has available a range of toothpastes which deliver oral health benefits. Adverse reactions to toothpastes are rare but should be considered in unexplained skin or respiratory allergies and gingival or lip lesions.

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Section: E978mentioning

confidence: 99%

Dentifrices; an update

Davies¹,

Scully²,

Preston³

2010

Med Oral

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“…25% when no mouthwash was used. Gingival indices and BOP were significantly reduced after use of either mouthwash, whereas they increased significantly in the absence of a mouthwash régimen [36][37][38][39][40][41][42][43][44][45][46][47][48].…”

Section: Discussionmentioning

confidence: 99%

Effects of a Novel Mouthwash on Plaque Presence and Gingival Health

Rodriguez¹,

Ajdaharian²

2017

Dentistry

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“…While some efficacy has been demonstrated for metal salts, a meta-analysis of stannous fluoride demonstrated significant heterogeneity in the findings of clinical studies (11) and most studies have shown zinc salts to be effective only when used in combination with other agents such as triclosan or chlorhexidine (10) . Triclosan has been shown to be effective against plaque and gingivitis in two systematic reviews (12)(13) ; however, a second systematic review with different inclusion/exclusion criteria failed to demonstrate 7 the same efficacy (11) . Furthermore, while triclosan is known to be safe for use in toothpaste formulations (14) , its use in a wide range of healthcare products have resulted in an accumulation of it and its breakdown products in the environment (15) .…”

Section: Introductionmentioning

confidence: 99%

Randomized controlled trial to study plaque inhibition in calcium sodium phosphosilicate dentifrices

Claydon

Hall²,

Hughes

et al. 2016

Journal of Dentistry

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms Methods:This was an exploratory, single-centre, examiner-blind, randomised, controlled, five treatment period, crossover, plaque re-growth study, with supervised use of study products. Twenty-three healthy adult volunteers were randomized to receive experimental 5% CSPS dentifrice; two marketed 5% CSPS dentifrices; active comparator mouthrinse and negative control dentifrice. At the start of each treatment period, zero plaque was established by dental prophylaxis and study products were dispensed as either dentifrice slurries or mouthrinse, twice daily for the next 4 days. No other forms of oral hygiene were permitted.After 96 hours, supra-gingival plaque was determined by plaque area (direct entry, planimetric method) and TPI. Changes from zero plaque were analysed.Results: For both measures, plaque re-growth at 96 hours was significantly lower following treatment with active comparator mouthrinse and significantly higher following treatment with the experimental 5% CSPS dentifrice, compared to all other treatments. There were no statistically significant differences between the three other treatments, except between the marketed 5% CSPS dentifrices, for overall plaque area. Conclusions:The comparator mouthwash was significantly more effective at preventing plaque accumulation than the dentifrice slurries. The three marketed dentifrices contained sodium lauryl sulphate and were more effective at reducing plaque re-growth than the experimental dentifrice formulated with a tegobetaine/adinol surfactant system. 5 Clinical relevanceThe CSPS containing dentifrices tested in this study showed no significant chemicaltherapeutic anti-plaque benefits compared to a negative control dentifrice. However, sodium lauryl sulphate-containing dentifrices controlled plaque more effectively than a tegobetaine/adinol-containing CSPS dentifrice suggesting that the impact of surfactant selection on anti-plaque activity of formulations warrants further investigation. NHS REC Reference: 12/SW/0294 6

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The effectiveness of self‐performed mechanical plaque control with triclosan containing dentifrices

Cited by 56 publications

References 35 publications

Dentifrices; an update

Dentifrices; an update

Effects of a Novel Mouthwash on Plaque Presence and Gingival Health

Randomized controlled trial to study plaque inhibition in calcium sodium phosphosilicate dentifrices

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