The Effectiveness Test of Oil Phase Ointment Containing Snakehead Fish (Channa striata) Extract on Open Stage II Acute Wounded Wistar Strain Male Rats

Daisa, Fransisca; Andrie, Mohamad; Taurina, Wintari

doi:10.22146/tradmedj.27920

Cited by 11 publications

(11 citation statements)

References 4 publications

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“…Kandungan protein albumin dan beberapa mineral seperti Zn, Cu, dan Fe mengandung senyawa penting bagi proses sintesis jaringan dan proses penyembuhan luka [24][25][26] . Asam amino utama pada ikan gabus yaitu glisin, alanin, prolin, arginin, leusin, isoleusin, serin, fenilalanin dan asam arakhidonat, berperan penting dalam sintesis kolagen dan reepitelisasi jaringan luka 26 .…”

Section: Potensi Ekstrak Ikan Gabus Pada Luka Diabetes Kandungan Kimiaunclassified

Potensi Ekstrak Ikan Gabus Terhadap Kesembuhan Luka Diabetes

Prayugo

Ichwan

Yamamoto

2021

JKS

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Abstrak. Luka diabetes merupakan luka kronis yang berdampak buruk bagi morbiditas, mortalitas, dan psiko-sosio-ekonomi penderita maupun keluarganya. Kondisi hiperglikemia mengakibatkan fase penyembuhan luka tidak berjalan normal. Ekstrak ikan gabus, yang dapat diberikan peroral maupun sebagai bahan kombinasi penutup luka berpotensi terhadap penyembuhan luka diabetes melalui peningkatan jumlah netrofil dan makrofag, neovaskularisasi. Selain itu, ekstrak ikan gabus meningkatkan jumlah fibroblas, deposisi kolagen, peningkatan re-epitelisasi, kekuatan regangan, dan kontraksi pada penyembuhan luka.

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Section: Potensi Ekstrak Ikan Gabus Pada Luka Diabetes Kandungan Kimiaunclassified

Potensi Ekstrak Ikan Gabus Terhadap Kesembuhan Luka Diabetes

Prayugo

Ichwan

Yamamoto

2021

JKS

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“…This test is also related to the convenience of using the ointment on the skin. A good ointment should have a pleasant odor, attractive color, and a soft texture to the skin (Daisa et al, 2017).…”

Section: Organoleptic Testmentioning

confidence: 99%

“…Snakehead fish ointment has been shown to have a healing effect on cuts (Daisa et al, 2017). Snakehead fish (Channa striata) contains amino acids and fatty acids which are important in the synthesis of collagen fibers, especially glycine, during the wound healing process.…”

Section: Introductionmentioning

confidence: 99%

Accelerated stability test of snakehead fish and kelulut honey ointment with CMC-Na as a binder

2021

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“…While omega-6 fatty acids, especially arachidonic acid, are the main substrates for the synthesis of eicosanoids which have pro and anti-inflammatory effects so that they can accelerate the inflammatory phase. (Daisa, et al, 2017). Collagen is one of the main connective tissues of animal protein and has been widely used as a biomedical material.…”

Section: Introductionmentioning

confidence: 99%

Effect of Addition of Tiger Grouper (Epinephelus fuscoguttatus) Skin Collagen to Cork Fish (Channa striata) Albumin Ointment on Closure of Cuts

Gunawan¹,

Suprayitno²

2021

IJSRP

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Ointments are semisolid preparations intended for topical application to the skin or mucous membranes. The ointment formulation requires the presence of an ointment base, the ointment base itself is an inactive carrier substance from topical preparations that can be in the form of liquid or solid which brings the active ingredient to contact with the skin. The ointment base used in an ointment formulation must be inert in other words not to damage or reduce the therapeutic effect of the drug it contains. The results of the first study showed that differences in collagen concentrations affected the quality of albumin ointment, namely pH, viscosity, protein content, fat content, and water content. The best albumin ointment was obtained at 0.8% collagen concentration with the following results pH 6.8, viscosity 27980 cP, protein content 1.34%, fat content 88.29%, and water content 2.24%. The results of the amino acid profile test showed that the highest result was Glycine 5618.18 mg/kg and the lowest was L-Tyrosine <66.93 mg/kg. Then continued in the second study, namely amino acid profile testing, zinc levels and experimental mice, the results of observations on day 3, day 5, and day 7 showed that the best concentration of albumin ointment treatment underwent a wound closure process. 75% on the 7th day.

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The Effectiveness Test of Oil Phase Ointment Containing Snakehead Fish (Channa striata) Extract on Open Stage II Acute Wounded Wistar Strain Male Rats

Abstract: The snakehead (Channa striata) contained fatty acids omega-3 and omega-6 are useful

Cited by 11 publications

References 4 publications

Potensi Ekstrak Ikan Gabus Terhadap Kesembuhan Luka Diabetes

Potensi Ekstrak Ikan Gabus Terhadap Kesembuhan Luka Diabetes

Accelerated stability test of snakehead fish and kelulut honey ointment with CMC-Na as a binder

Effect of Addition of Tiger Grouper (Epinephelus fuscoguttatus) Skin Collagen to Cork Fish (Channa striata) Albumin Ointment on Closure of Cuts

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