The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation

Zhang, Zejun; Zhu, Huawei; Zheng, Yating; Zhang, Lanyue; Wang, Xiaoling; Luo, Zhen; Tang, Jian; Lin, Li; Du, Zhiyun; Dong, Chang‐Zhi

doi:10.1016/j.jphotobiol.2020.111964

Cited by 46 publications

(41 citation statements)

References 43 publications

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“…Elastin is an inert protein that forms during early development and is not replenished, so any loss in elastin that occurs throughout life tends to be irreversible (91). In photoaged skin, collagen and elastin content are both reduced by ~50%, which means that hydration, tensile strength and elasticity are compromised (92). The dermis also hosts sweat glands that, although they may show atrophy, generally continue to function in elderly individuals.…”

Section: Skin Changes Associated With Agingmentioning

confidence: 99%

Bullous pemphigoid: An immune disorder related to aging (Review)

et al. 2021

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Section: Skin Changes Associated With Agingmentioning

confidence: 99%

Bullous pemphigoid: An immune disorder related to aging (Review)

et al. 2021

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“…Their low molecular weight has been reported to increase their bioavailability compared to their parent proteins. The utilization of collagen peptides in food supplements, cosmetic and pharmaceutical products is rapidly increasing [31,32]. The incorporation of collagen peptides in commercial cosmetic formulations has recently become exceptionally trendy due to their anti-aging properties.…”

Section: Introductionmentioning

confidence: 99%

New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application

Sharkawy

Barreiro

Rodrigues

2021

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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“…Production of collagen and elastin is essential for the recovery of skin damage caused by photoaging [ 48 ]. UV rays accelerate skin aging by destroying collagen, elastin, and hyaluronic acid, which are important for skin elasticity [ 49 , 50 ]. Elastin and collagen are the major factors associated with skin elasticity and wrinkles [ 49 ].…”

Section: Discussionmentioning

confidence: 99%

“…UV rays accelerate skin aging by destroying collagen, elastin, and hyaluronic acid, which are important for skin elasticity [ 49 , 50 ]. Elastin and collagen are the major factors associated with skin elasticity and wrinkles [ 49 ]. As aging progresses, the synthesis of type I procollagen in the skin decreases, and the activity of MMP-1 increases [ 51 ].…”

Section: Discussionmentioning

confidence: 99%

The Metabolite Profile in Culture Supernatant of Aster yomena Callus and Its Anti-Photoaging Effect in Skin Cells Exposed to UVB

Kim

Seo

Lee

et al. 2021

Plants

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Aster yomena (A. yomena) extract has anti-inflammatory, antioxidant, anti-asthma, and anti-atopic effects. However, the commercial use of A. yomena extract requires a long processing time with specific processing steps (including heat treatment and ethanol precipitation), and there are various environmental problems. We aimed to build a system to produce A. yomena extract by culturing the callus in a bioreactor that can allow rapid process scale-up to test the effect of extract (AYC-CS-E) isolated from culture supernatant of A. yomena callus on photoaging of human keratinocytes (HaCaT) caused by ultraviolet B (UVB) exposure. Through screening analysis based on ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MS), 17 major metabolites were tentatively identified from AYC-CS-E for the first time. The suppression of cell proliferation caused by UVB was effectively alleviated in UVB-irradiated HaCaT cells treated with AYC-CS-E. Treatment with AYC-CS-E strongly induced the formation of type I procollagen and the inhibition of elastase in UVB-irradiated HaCaT cells and significantly reduced the expression of matrix metalloproteinase (MMP)-1. In addition, treatment of UVB-irradiated HaCaT cells with AYC-CS-E effectively improved various factors associated with an inflammatory reaction, skin damage recovery, skin moisture retention, and hyper-keratinization caused by photoaging, such as reactive oxygen species (ROS), pro-inflammatory cytokines, transforming growth factor beta (TGF-β), MMP-3, MMP-9, filaggrin, hyaluronic acid synthase 2 (HAS-2), keratin 1 (KRT-1), nuclear factor-kappa B (NF-κB), and nuclear factor erythroid 2-related factor 2 (Nrf2) at the gene and protein levels. These results suggest that AYC-CS-E can be used as a cosmetic ingredient for various skin diseases caused by photoaging, and the current callus culture system can be used commercially to supply cosmetic ingredients.

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The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation

Cited by 46 publications

References 43 publications

Bullous pemphigoid: An immune disorder related to aging (Review)

Bullous pemphigoid: An immune disorder related to aging (Review)

New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application

The Metabolite Profile in Culture Supernatant of Aster yomena Callus and Its Anti-Photoaging Effect in Skin Cells Exposed to UVB

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