2012
DOI: 10.14476/jomp.2012.37.1.027
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The Effects of Corticosteroid Solutions in OLP Patients

Abstract: 까지 부산대학교 치과병원 구강내과에서 구강편평태선으로 진단받은 환자들 중 corticosteroid 가글용액을 처방받은 환자들 총 180명의 환자기록을 조사하였다. 사용된 두 종류의 가글용액은 각각 dexamethasone(dexamethasone disodium phosphate, 0.05%)과 prednisolone(solondo Ⓡ )을 포함하는 용액이었으며 약물 사용 후 증상의 완화 및 재발의 시기를 기록하 여 분석하였다. Dexamethasone gargle(dexa gargle) 처방군은 33명(여성 25명, 남성 8명), prednisolone gargle(solon gargle) 처방군은 147명(여성 114명, 남성 33명)이었으며 환자군의 평균연령대는 50대였다. 약물투여 후 초기 2주이내에 증상이 호전 된 경우는 dexa gargle을 사용한 환자군에서 유의성 있게 나타났으나 증상재발의 경우는 두가지 가글용액의 차이가 나타나 지 않았다. 구강편평태선 환자에 대한 도포용 스테로이드 가글을 이… Show more

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“…Dexamethasone is a corticosteroid that has 26.6 and 6.6 times stronger anti-inflammatory and immunosuppressant effects than cortisol and prednisone, respectively. Owing to its anti-inflammatory effects, dexamethasone is also used for autoimmune conditions such as rheumatoid arthritis and bronchospasm, for the control of side effects after chemotherapy in cancer patients [ 11 ], and as a gargle solution in dentistry to alleviate the symptoms of oral lichen planus [ 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…Dexamethasone is a corticosteroid that has 26.6 and 6.6 times stronger anti-inflammatory and immunosuppressant effects than cortisol and prednisone, respectively. Owing to its anti-inflammatory effects, dexamethasone is also used for autoimmune conditions such as rheumatoid arthritis and bronchospasm, for the control of side effects after chemotherapy in cancer patients [ 11 ], and as a gargle solution in dentistry to alleviate the symptoms of oral lichen planus [ 12 ].…”
Section: Introductionmentioning
confidence: 99%