The relevance of our study is determined by the global transition to a digital economy, a knowledge-based society. Today, specialists with information and communication competencies (and a special role in their education belongs to mathematics) are becoming in high demand. In this regard, this paper is devoted to the theoretical justification and development of the methodology for using information and communication technologies (ICT) in teaching mathematics in the context of digitalization of education. The implementation of the methods of complex and comparative analysis allowed us to reveal aspects of using ICT in the process of teaching mathematics, as well as to present technologies of mixed learning based on ICT. The authors conclude that the use of ICT in mathematics helps to effectively increase students' motivation, to involve students in active cognitive activity, and to construct an individual educational trajectory. The results of experimental work confirm that the effectiveness of using ICT in teaching mathematics in higher education institutions depends on the educator's competence in the field of ICT.