The Effects of Hijikia fusiforme on Serum Lipid Levels in Ovariectomized Rats

김정엽,; 김미향,

doi:10.5352/jls.2005.15.2.242

Cited by 2 publications

(2 citation statements)

References 9 publications

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“… * blanks indicate no data available at this time for these compounds on this item. Seco: secoisolariciresinol, Mat: matairesinol, Lar: lariciresinol, Pino: pinoresinol, Med: medioresinol, Syr: syringaresinol, all as aglycones.갱년기가 시작되어 신체조직의 노화(Kim and Kim, 2005)와 함께 난소 기능 저하로 에스트로겐의 분비가 감소함으로써 발생하는 신체변화로 인해 혈중 LDL-콜레스테롤이 증가하여 심혈관계질환의 발생빈도가 증가한다…”

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Chemical Properties of Lignans, Their Effects on Human Health, and the Enhancement of Milk Function of Lignans

Hwang¹,

Yoon²,

Shin³

2018

J. Milk Sci. Biotechnol.

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This review discusses the characteristics of major lignans and related studies and provides a basis for future studies. Lignans are present in various food products consumed daily, such as flaxseed and other seeds, vegetables, fruits, and beverages including coffee, tea, and wine. Lignans are natural phytoestrogens with a structure similar to that of secoisolariciresinol (Seco), mataireinol (Mat), pinoresinol (Pin), medioresinol (Med), lariciresinol (Lari), and syringaresinol, which is then converted to enterodiol (END) and enterolactone (ENL), which are mammalian lignans and the primary biologically active enterolignans, by the intestinal microflora. The associations between lignans and a decreased risk of cardiovascular disease are promising; however, they are not yet well-established, probably owing to low lignan intake in habitual Western diets. Nonetheless, these associations were more prominent at the higher doses in interventional studies. Many studies on humans and animals have reported the benefits of lignan consumption in protecting against CVD and metabolic syndrome by reducing lipid and glucose concentrations. END and ENL reportedly exert protective effects including phytoestrogenic, antioxidant, anti-inflammatory, and anticancer effects through various mechanisms. Moreover, lignans reportedly exert beneficial effects in breast, colon, and prostate cancer and osteoporosis have reported that. However, future studies are required to confirm the association between lignan and disease.

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Chemical Properties of Lignans, Their Effects on Human Health, and the Enhancement of Milk Function of Lignans

Hwang¹,

Yoon²,

Shin³

2018

J. Milk Sci. Biotechnol.

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“…질병 치료, 예방 및 건강증진 등 생리활성을 지닌 기능성 물질의 탐색은 식 품․의약품 시장에서 높은 성장가능성을 기대하는 산업분야 로 떠오르고 있으며, 특히 천연물 유래 기능성 물질은 화학 합성품에 비해 각종 질병에 효과적인 경우가 많고 낮은 독성 과 부작용에 대한 인식으로 소비자들에게 높은 선호도를 보이 고 있다 [27]. 해조류 유래 estrogen 대체효과에 대한 연구는 다양하게 이루어지고 있으나 [19,23,36,43], 앞으로도 지속적 인 연구가 필요하다.…”

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The Effects of Seaweed Gongjindan on Estrogen like Activities, Platelet Aggregation and Serum Lipid Levels in Ovariectomized Rats

전명정¹,

김서연²,

김보경³

et al. 2013

Journal of Life Science

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Estrogen like activities were evaluated using ethanol and hot water extracts of gongjindan (GJD) and 3 types of brown algae by an in vitro detection system. Laminaria japonica and Undaria pinnatifida represented statistically significant (p<0.001) estrogen like activities, while GJD and Ecklonia stolonifera did not. Furthermore, activities of hot water extracts (500 μg/ml) of Laminaria japonica and three mixture (Ecklonia stolonifera : Undaria pinnatifida : Laminaria japonica , 1: 1: 1) were stronger than that of 10 -7 M 17β-estradiol. These results suggest that Laminaria japonica contain estrogen like compounds. Based on these results, the prepared seaweed GJD were used for animal experiments about the effects on inhibition of platelet aggregation and serum lipid levels in ovariectomized rats. 9-week Old female SD-rats were randomly assigned to 3 groups as sham-operated rats, ovariectomized rats and ovariectomized rats that were treated with GJD. The rats were placed on prescribed diets for 5 weeks following ovariectomy. Total cholesterol and triglyceride contents on serum decreased in the SHAM group compared to the OVX-CON group. 5 weeks feeding of GJD resulted in significant lowering of triglyceride and a decreasing tendency of total cholesterol level. The level of HDL-cholesterol on serum increased significantly by feeding diets containing the GJD. The ability of platelet aggregation of group treated with GJD was less than that of the OVX-CON group. These results suggest that the beneficial effects of seaweed gongjindan may be used to improve menopausal syndrome.

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The Effects of Hijikia fusiforme on Serum Lipid Levels in Ovariectomized Rats

Cited by 2 publications

References 9 publications

Chemical Properties of Lignans, Their Effects on Human Health, and the Enhancement of Milk Function of Lignans

Chemical Properties of Lignans, Their Effects on Human Health, and the Enhancement of Milk Function of Lignans

The Effects of Seaweed Gongjindan on Estrogen like Activities, Platelet Aggregation and Serum Lipid Levels in Ovariectomized Rats

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