The Effects of Immobilization on the Ultrastructure and Mechanical Properties of the Medial Collateral Ligament of Rats

Effect of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization on Tendon-Bone Healing After ACL Reconstruction in a Rat Model

“…In contrast to the results of this work, previous studies demonstrated the detrimental effect of stress deprivation on the biomechanical properties of tendons and ligaments [21][22][23][24] . Our findings, however, are consistent with recent studies that examined tendon-to-bone healing in a rat rotator cuff model 6,25 , in which, at eight weeks postoperatively, there was no change in structural properties according to activity level 6 .…”

Imaging Studies of the Mechanical and Architectural Characteristics of the Human Achilles Tendon in Normal, Unloaded and Rehabilitating Conditions

“…Effect of Unloading on Stress-strain curve of the Achilles tendon: at pre-suspension (Pre), at post-suspension (P0), and after 6 wk of physical rehabilitation (P6) for five subjects (from Shin et al 2008a). This assumption is supported by some relevant findings including an increase in rat collagen fiber proportion (Binkley & Peat 1986) and CSA of ewe spinal ligament (Kotani et al 1998) as a result of chronic unloading. However, animal data on the effects of chronic unloading on collagen fibril size, density, and number are conflicting.…”

Effect of Immediate and Delayed High-Strain Loading on Tendon-to-Bone Healing After Anterior Cruciate Ligament Reconstruction

“…It has been well established that mechanical stimuli are essential for the normal maintenance of ligament, tendon, and bone integrity [22][23][24][25][26][27][28][29] . Stress deprivation decreases collagen organization and ultimate tissue strength 27 .…”