The Effects of Isoflurane and Isoflurane-Nitrous Oxide Anesthesia on Brainstem Auditory Evoked Potentials in Humans

Manninen, Pirjo; Lam, Arthur M.; Nicholas, James F.

doi:10.1213/00000539-198501000-00009

Cited by 68 publications

(32 citation statements)

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“…Porkkala and Lam showed that nitrous oxide 60% reduced the amplitude of the somato-evoked response without affecting the latency [11,14] and a similar pattern applied to the auditory evoked response, but these results were inconclusive. Manninen and Sebel studied the early brainstem response and found no major effects due to nitrous oxide [15,16]. Kobuku studied the effects of nitrous oxide on the middle latency auditory evoked response in the 10-100 ms time domain and found a significant reduction in amplitude following inhalation of nitrous oxide 30% for 30 min but no change in latency [5].…”

Section: Discussionmentioning

confidence: 99%

The effects of nitrous oxide on the auditory evoked potential index during sevoflurane anaesthesia

2002

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SummaryWe have studied the effects of nitrous oxide on the auditory evoked response index (AAI TM -index) derived from the A-line monitoring device during sevoflurane anaesthesia in 21 patients undergoing minor ambulatory surgery. During sevoflurane anaesthesia with an AAI TM -index < 30, the addition or withdrawal of nitrous oxide in a concentration of 66% end tidal did not show any linear dose dependent change in AAI TM -index. However, comparing nitrous oxide > 40% to nitrous oxide < 10% end tidal concentration the AAI TM -index did decrease, p < 0.05. The AAI TM -index is either non-linear at deeper anaesthetic levels or is insensitive to the anaesthetic effects of nitrous oxide in terms of MAC-multiples.

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Section: Discussionmentioning

confidence: 99%

The effects of nitrous oxide on the auditory evoked potential index during sevoflurane anaesthesia

2002

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“…Central conduction time also is altered by these drugs. The volatile agents halothane, enflurane and isoflurane alter BAEP [18], but BAEP is more resistant to i.v. anaesthetic agents.…”

Section: Discussionmentioning

confidence: 99%

Auditory Evoked Potentials During Propofol Anaesthesia in Man

Chassard

Colson

Banssillon

et al. 1989

British Journal of Anaesthesia

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“…Inhalational anesthetics can statistically but not clinically significantly increase latency of wave V, as these latency changes are less than 0.75 ms (Legatt 2002). Nitrous oxide causes no change in either amplitude or latency of signals (Manninen et al 1985). Continuous infusions of intravenous anesthetics or narcotics have minimal effects of BAEP latency or amplitude.…”

Section: Brainstem Auditory Evoked Potentialsmentioning

confidence: 93%

Intraoperative Monitoring for Cranial Base Tumors

Akagami

Dong

Huttunen

2011

Tumors of the Central Nervous System, Volume 4

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Intraoperative neurophysiological monitoring is used to guide surgery and predict the postoperative neurological function of patients. Surgery for basal neurosurgical tumors is fraught with difficulties due to the important neurovascular anatomy at risk. During these often long surgical cases, the function of the nerves and long tracts at risk can be monitored, giving the surgeon near real time feedback on how the patient is doing and what functions if any are being affected. This information is useful in trying to reduce and prevent injuries for quality control and improve patient outcomes. With the advent and effectiveness of alternative treatment strategies for many of these tumors, such as focused stereotactic radiation as primary treatment or surgery plus radiation (for planned subtotal resections), surgical outcomes need to be looked at critically; it becomes necessary to be able to perform these operations with minimal morbidity. Intraoperative monitoring is an adjunct to surgery that aids the surgeon in procedures for patients with these difficult tumors.

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The Effects of Isoflurane and Isoflurane-Nitrous Oxide Anesthesia on Brainstem Auditory Evoked Potentials in Humans

Cited by 68 publications

References 0 publications

The effects of nitrous oxide on the auditory evoked potential index during sevoflurane anaesthesia

The effects of nitrous oxide on the auditory evoked potential index during sevoflurane anaesthesia

Auditory Evoked Potentials During Propofol Anaesthesia in Man

Intraoperative Monitoring for Cranial Base Tumors

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