1990
DOI: 10.1016/s0002-8703(05)80084-5
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The effects of long-term antithrombotic treatment on left ventricular thrombi in patients after an acute myocardial infarction

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Cited by 38 publications
(6 citation statements)
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“…LV thrombus resolution was also more common in individuals who received aspirin at a higher dose than used in contemporary practice (600 mg daily) compared with no warfarin or antiplatelet therapy (45% versus 10%; P <0.01). 62 In a meta-analysis of 7 observational studies including 270 patients with LV anterior wall MI and LV thrombus, systemic anticoagulation was associated with a lower risk of embolic events (OR, 0.14 [95% CI, 0.04–0.52]). 41 In a more recent study, among patients treated with warfarin, greater time in therapeutic range (TTR) was associated with less systemic thromboembolism (TTR ≥50%, 2.9%; TTR <50%, 19%; P =0.036).…”
Section: Treatment Of LV Thrombus After Acute Mimentioning
confidence: 99%
“…LV thrombus resolution was also more common in individuals who received aspirin at a higher dose than used in contemporary practice (600 mg daily) compared with no warfarin or antiplatelet therapy (45% versus 10%; P <0.01). 62 In a meta-analysis of 7 observational studies including 270 patients with LV anterior wall MI and LV thrombus, systemic anticoagulation was associated with a lower risk of embolic events (OR, 0.14 [95% CI, 0.04–0.52]). 41 In a more recent study, among patients treated with warfarin, greater time in therapeutic range (TTR) was associated with less systemic thromboembolism (TTR ≥50%, 2.9%; TTR <50%, 19%; P =0.036).…”
Section: Treatment Of LV Thrombus After Acute Mimentioning
confidence: 99%
“…RCT [183] In patients with acute anterior MI subcutaneous heparin at a dose of 12,500 U BID was more effective preventing LVT than 5,000 units BID Kouvaras, 1990…”
Section: Vitamin K Antagonist (Vka)mentioning
confidence: 99%
“…• Intravenous thrombolytics have been used to lyse LVT [34] but carry the risk of precipitating embolic events and are not recommended. • Surgical removal of LVT has been performed, but should be reserved for recurrent embolic events in the face of persistent LVT despite therapeutic anticoagulation when accompanied by other indicated cardiac surgery [35].…”
Section: Pharmacologic Prevention Of Lvt In Dcmmentioning
confidence: 99%