The Effects of Parenteral Iron Administration on Thyroid Hormones, Hematology, Oxidative Stress Characteristics, Performance, and Health in Neonatal Holstein Calves

Khaleghnia, Narges; Mohri, Mehrdad; Seifi, Hesam A

doi:10.1007/s12011-020-02293-7

Cited by 7 publications

(6 citation statements)

References 38 publications

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“…Lung ultrasound scoring methods can be used to semiquantify the severity of lung disease [7]. in diagnosing and monitoring neonatal lung diseases, the accuracy is also high, but ultrasound diagnosis of neonatal respiratory distress syndrome also has certain limitations: (1) lung ultrasound diagnosis is highly subjective, and if the operator lacks training or experience, it is difficult to ensure the accuracy of the diagnosis results, and the operator needs to undergo formal training; (2) subcutaneous emphysema will affect the performance of the ultrasound, and the lung ultrasound cannot be conducted for the diagnosis of emphysema; (3) the thicker fat layer in obese children will affect the quality of ultrasound images [12].…”

Section: Literature Reviewmentioning

confidence: 99%

[Retracted] Clinical Value and Imaging Features of Bedside High‐Frequency Ultrasound Imaging in the Diagnosis of Neonatal Pneumonia

Zhu¹,

Chen²,

Jiang³

2022

Contrast Media & Molecular Imaging

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The aim is to solve the problem of the urgent need of a nonradiation, noninvasive, and simple-to-operate diagnostic method for neonatal pneumonia that can indicate the severity of the disease and dynamically monitor the outcome of the disease. The authors propose a bedside high-frequency ultrasound technique based on methods for evaluation in the detection and treatment of neonatal pneumonia. The results obtained are as follows: the sensitivity of neonatal lung ultrasound in the diagnosis of neonatal pneumonia was 96.6%, the specificity was 93.3%, the positive predictive value was 93.5%, and the negative predictive value was 96.5%. The sensitivity of chest X-ray in the diagnosis of neonatal pneumonia was 93.3%. Compared with the lung ultrasound and chest X-ray in the diagnosis of neonatal pneumonia, the two had a good correlation. The neonatal respiratory score was positively correlated with the lung ultrasound score, and the higher the lung ultrasound score, the more severe the disease. The score decreased by 35% after 3 days of treatment and 68% after 7 days of treatment, indicating that the lung high-frequency ultrasound score can be very effective in characterizing the treatment situation. It has been demonstrated that the lung ultrasound can be used as an imaging method for the diagnosis of neonatal pneumonia. The higher the lung ultrasound score, the more severe the disease, and the lung ultrasound score was positively correlated with the disease severity. With dynamic monitoring of the lung ultrasound and the gradual improvement of clinical symptoms after treatment, the lung ultrasound score gradually decreased; therefore, the lung ultrasound can be used for re-examination of neonatal pneumonia to evaluate the treatment effect and guidance.

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Section: Literature Reviewmentioning

confidence: 99%

[Retracted] Clinical Value and Imaging Features of Bedside High‐Frequency Ultrasound Imaging in the Diagnosis of Neonatal Pneumonia

Zhu¹,

Chen²,

Jiang³

2022

Contrast Media & Molecular Imaging

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“…The various effects of iron supplementation on lambs’ performance may be due to the different agents including iron storage, dosage, method of iron supplementation, and the level of dietary iron [ 37 ]. For instance, one of the effective factors in reducing feed consumption when using high levels of iron is due to reduced palatability of the diet [ 35 ].…”

Section: Resultsmentioning

confidence: 99%

“…Ceppi and Blum [ 73 ] indicated that the levels of T3 were significantly influenced by iron consumption in calves, but there was no effect on the levels of T4. In another study, no difference was observed between experimental groups with respect to thyroid metabolism [ 37 ].…”

Section: Resultsmentioning

confidence: 99%

Milk Supplemented with Organic Iron Improves Performance, Blood Hematology, Iron Metabolism Parameters, Biochemical and Immunological Parameters in Suckling Dalagh Lambs

Asadi

Toghdory

Hatami

et al. 2022

Animals

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This study was conducted to investigate the effect of milk supplemented with organic iron on performance, blood hematology, iron metabolism parameters, biochemical and immunological parameters in suckling lambs. Thirty-six newborn Dalagh lambs were randomly divided into three groups with 12 replications. The control group was fed with milk without organic iron. The other two groups were fed milk supplemented with 25 and 50 mg/d organic iron, respectively. During the experiment, increased daily weight gain and total body weight were observed in the iron-supplemented groups. An increase in the levels of red blood cell, hemoglobin, hematocrit, mean corpuscular hemoglobin, and mean corpuscular concentration in iron supplemented groups was indicated. Consumption of organic iron caused a significant decrease in plasma copper concentration. Total antioxidant status level was lower, but levels of glutathione peroxidase, superoxide dismutase, and catalase were higher in iron supplemented groups. In organic iron supplemented groups, insulin and thyroid hormones levels were significantly increased, and glucose level was significantly decreased. In organic iron supplemented groups, alkaline phosphatase level significantly increased, and aminotransferase level significantly decreased. Overall, the use of organic iron in the milk improved the performance and health in suckling lambs, and since a lower level of supplementation is naturally preferable, supplementation of milk with 25 mg/d organic iron is recommended.

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“…Calves fed whole milk containing limited amounts of iron may be at risk of developing iron deficiency and ensuing detrimental effects 1 . Numerous studies have aimed at untangling the regulation of early life iron homeostasis in calves raised in different production systems, fed varying types and amounts of feed with differing iron content 2‐9 . To the authors’ knowledge, no studies exist evaluating the iron homeostasis in calves fed an elevated plane of nutrition with high average daily weight gains (ADG) beyond 800 g/day.…”

Section: Introductionmentioning

confidence: 99%

“…tion systems, fed varying types and amounts of feed with differing iron content. [2][3][4][5][6][7][8][9] To the authors' knowledge, no studies exist evaluating the iron homeostasis in calves fed an elevated plane of nutrition with high average daily weight gains (ADG) beyond 800 g/day. Progress in understanding iron homeostasis was made in recent decades, and it is now evident that the evaluation of the iron status of an individual based on serum iron concentration can be misleading, as this parameter is subject to a large degree of variation and is greatly influenced by inflammation commonly encountered in young and growing calves.…”

Section: Introductionmentioning

confidence: 99%

Effects of oral or parenteral iron supplementation on haematological parameters, blood iron status and growth in newborn calves fed milk replacer

et al. 2023

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BackgroundThis study aimed to assess the influence of early life iron supplementation on the haematological parameters of calves fed milk replacer on a high plane of nutrition.MethodsThirty calves were allocated to receive either a sham treatment (CON), injection of 1000 mg Fe3+ (INJ) or oral administration of 1050 mg Fe3+ (ORAL), all administered less than 1 hour after birth. Blood was obtained before treatment, on days 1, 3, 5 and 7 of life and once weekly until week 9. Samples were analysed for haemoglobin (Hb), packed cell volume (PCV) and estimated transferrin saturation (%TSAT).ResultsThe Hb and PCV of calves in the INJ and ORAL groups were above the values of those in the CON group throughout the study. Hb and PCV of the CON group remained within the reference range for calves. The %TSAT exceeded reported ranges in the ORAL group in the first week. Values for the CON group were below the INJ and ORAL groups throughout the entire study. Average daily gain did not differ between treatments.LimitationsThe sample size was insufficient to assess the influence of iron supplementation on disease development. Furthermore, the study was set in a controlled environment and not performed under field conditions.ConclusionsOral and subcutaneous iron administration had similar effects on haematological development but resulted in numerically different transferrin saturation. Control animals showed lower Hb and PCV but did not develop overt anaemia.

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The Effects of Parenteral Iron Administration on Thyroid Hormones, Hematology, Oxidative Stress Characteristics, Performance, and Health in Neonatal Holstein Calves

Cited by 7 publications

References 38 publications

[Retracted] Clinical Value and Imaging Features of Bedside High‐Frequency Ultrasound Imaging in the Diagnosis of Neonatal Pneumonia

[Retracted] Clinical Value and Imaging Features of Bedside High‐Frequency Ultrasound Imaging in the Diagnosis of Neonatal Pneumonia

Milk Supplemented with Organic Iron Improves Performance, Blood Hematology, Iron Metabolism Parameters, Biochemical and Immunological Parameters in Suckling Dalagh Lambs

Effects of oral or parenteral iron supplementation on haematological parameters, blood iron status and growth in newborn calves fed milk replacer

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