The effects of partial sleep deprivation and the sub-maximal NDKS exercise testing protocol on S-Klotho and hemodynamic responses in men

Abstract

The purpose of the study was to examine the influences of partial sleep deprivation on young healthy trained men's responses to the NDKS sub-maximal exercise testing protocol.Methods: 20 males 21.6±1.82 years of age, volunteered to participate in this study. Subjects underwent two submaximal NDKS exercise tests, once after 7-8 hours of sleep, and once after staying awake for 20 hours. S-klotho, blood pressure, heart rate, fasting blood glucose, and Lactate were obtained at baseline, immediate-post, and post a dynamic recovery of 3 minutes.Results: S-klotho at baseline was 430.31±12.62 (pg•mL -¹). Significant differences were found between conditions regarding immediate-post s-klotho concentration (557.97±20.08 vs 494.85±11.57 (pg•mL -¹), respectively, F(39,1) = 144.648, p ≤ 0.01). Significant differences were found between conditions regarding post-recovery s-klotho concentration (453.29±4.34 vs 471.48±8.89 (pg•mL -¹), respectively, F (39,1) = 64.146, p ≤ 0.01). Conclusions:while not all comparisons for data obtained were significantly different, partial sleep deprivation induced favorable responses while non-partially sleep deprived. All data show that while partially sleep deprived, the subjects were less efficient.