To achieve the energy conservation and sustainable development, the prewhirl regulation by inlet guide vanes is proposed and rapidly developed for the compressor and pump. The inlet guide vanes change the flow pattern at the impeller inlet especially the velocity circulation, and then influence the performance of compressor and pump. This paper presents and discusses researches on the prewhirl regulation by inlet guide vanes. Researches include mechanism analysis of prewhirl regulation, experimental and numerical studies on the flow field, performance of compressor and pump with inlet guide vanes, influence of geometric parameters on performance of inlet guide vanes, and failure mode analysis and corresponding flow control methods.