Objectives: This study was conducted to examine the effects of digital empowerment teacher training program applying virtual reality on digital media literacy, teacher efficacy, and problem-solving ability of school nurse.Methods: A quasi -experimental study of pre- and post-experimental design was performed on 47 school nurse located in K city and the developed digital empowerment teacher training program was implemented. The data collection period is July 27, 2021, and the collected data is collected using the SPSS 18.0 program. Paired t-test were analyzed.Results: According to the results of the effect, it was found that there was a significant difference in digital media literacy and problem-solving ability.Conclusions: The digital empowerment teacher training program developed in this study can be used as an effective program to enhance the digital media literacy and problem-solving ability of school nurse.