The Effects of Tissue Heterogeneitieson Dose Distribution of Iridium-192 Source in Brachytherapy Treatments

Zabihzadeh, Mansour; Yadollahpour, Ali; Kargar, Leila

doi:10.13005/bpj/404

Cited by 5 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…radially in relation to the size of the air pocket. Outcome of our results are in at agreements with the above published literature (Celik et al, 2018;Zabihzadeh et al, 2013;Terribilini et al, 2007;Chandola et al, 2010).…”

Section: Author Contribution Statementsupporting

confidence: 93%

“…The most important point of their results is that the PDD curve of the radiation in the air medium through to the water medium is different from the only water medium. Zabihzadeh et al, (2013) have found air heterogeneity dose increases as 9.11-10.2%, 9.11-10.0%, 8.62-10.08% , air at a distance of 10 mm from the source produced heterogeneity that was 7% higher than the corresponding value of the control water medium (Terribilini et al, 2007). In a similar study, Chandola et al, (2010) have found that the corresponding doses behind heterogeneities were 5.5-6.5% higher and 4.5-5% lower than water phantom values in the presence of air and cortical bone, respectively.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Dosimetric Study to Estimate Deviations in Delivered Radiation Dose due to Occluded Air Spaces in Vaginal Vault Brachytherapy Applications

Srinivas

Banerjee

Lobo

et al. 2023

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Background: To develop a dosimetric tool to estimate the dose delivered in the presence of air pockets with EBT3 film while simulating the conditions of vaginal vault brachytherapy (VVBT) with 3.0 diameter cylindrical applicator at a prescription dose distance of 5mm from the surface of it. Materials and Method: Six acrylic plates (10 cm x 10 cm, 0.5 cm thick) with four different types of slots were designed and produced locally. They can hold a cylindrical vaginal brachytherapy applicator in the centre, air equivalent material from the applicator’s surface [(sizes 4.5 mm (A), 3.0 mm (B), and 2.0 mm (C)], EBT3 film at the prescribed dose distance, and holder rods. Plates were layered together with acrylic rods and assembled in a holding box in a water phantom. Three treatment plans done in TPS with prescription doses of 2 Gy, 3 Gy, and 4 Gy at 5.0 mm with a treatment length of 6 cm, and were executed in Co-60-based HDR brachytherapy unit (M/s SagiNova, Germany) with & without the placement of air equivalent material, and the dose received at slot locations A, B, & C were noted. Results: The mean percentage deviation of measured dose without and with presence of air pocket at A, B and C was 13.9%, 11.0% and 6.4% respectively for all dose prescriptions. As the air pocket size expanded radially from 2.0 mm to 4.5 mm, the increase in dosage ranged from 6.4% to 13.9% which was due to the fact that the film was held at dosage prescription distance and the lack of attenuation of photons radially through air pocket. Conclusions: The present study can be carried out with a 3D printed phantom that simulates VVBT application having air pockets of different dimensions at different locations and also can be analyzed with Monte Carlo simulations.

show abstract

Section: Author Contribution Statementsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Dosimetric Study to Estimate Deviations in Delivered Radiation Dose due to Occluded Air Spaces in Vaginal Vault Brachytherapy Applications

Srinivas

Banerjee

Lobo

et al. 2023

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

show abstract

“…Anatomically, such disruptions cause a breakdown in dose distribution by increasing the PDD values within the BT treatment area. 15,16 Zabihzadeh et al 17 have found air heterogeneity dose increases as 9•11-10•2, 9•11-10•0, 8•62-10•08 and 8•5-10•07%, respectively, for 5, 10, 20 and 30 mm distances from the source. In a study by Terribilini et al, 18 air at a distance of 10 mm from the source produced heterogeneity that was 7% higher than the corresponding value of the control water medium.…”

Section: Discussionmentioning

confidence: 97%

Evaluation of air cavities on dose distributions with air-filled apparatuses having different volumes using Gafchromic EBT3 films in brachytherapy

Celik

Olacak

et al. 2018

J Radiother Pract

View full text Add to dashboard Cite

AimThe data used in brachytherapy planning are obtained from homogeneous mediums. In practice, the heterogeneous tissues and materials affect the dose distribution of brachytherapy. It is aimed to investigate the effect of air cavities on brachytherapy dose distribution using a specially designed device.Material and methodsIn this study, the special device designed with different volumes of air and water to be irradiated and measured at different depths using EBT3 Gafchromic films. EBT3 Gafchromic films were preferred for this study because they can be cut to the shape of the experimental geometry, are water resistance and double directional usability.ResultsIn our study, sudden dose increases and decreases were observed at the water–air–water interfaces. Increases were 9, 11·8 and 15% in the 13, 18 and 22 mm apparatus, respectively. These effects were expected and the results were consistent with the literature and within the tolerance limits stated in the clinical dose guidelines. The most important result is that the percent depth–dose curve of the radiation passing through the air to the water and only passing through the water medium is different. The average differences were 1·97, 2·97 and 2·31% for the 13, 18 and 22 mm apparatus, respectively.ConclusionAlthough the effect of heterogeneity may be neglected according to clinical guidelines, it is suggested that the dose effect of heterogeneity is taken into account so that the dose can be estimated sensitively. Brachytherapy plans using dose data without considering air gaps may cause erroneous dose distributions due to heterogeneity of tissue.

show abstract

“…16 The function of this software is based on the AAPM TG-43 protocol in which all of the tissues are considered to be water equivalent. 17,18 On the other hand, the difference between mass absorption coefficient and electron density of different types of tissues and water 19 can introduce significant errors in the treatment planning procedure which will finally influence the accuracy of performed treatment. 20 One of the evident examples of this noncompliance is seen in esophageal brachytherapy.…”

Section: Introductionmentioning

confidence: 99%

Evaluating the performance of TG-43 protocol in esophageal HDR brachytherapy viewpoint to trachea inhomogeneity

Daghigh

Baghani

Aghamiri

et al. 2017

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

show abstract

The Effects of Tissue Heterogeneitieson Dose Distribution of Iridium-192 Source in Brachytherapy Treatments

Cited by 5 publications

References 18 publications

Dosimetric Study to Estimate Deviations in Delivered Radiation Dose due to Occluded Air Spaces in Vaginal Vault Brachytherapy Applications

Dosimetric Study to Estimate Deviations in Delivered Radiation Dose due to Occluded Air Spaces in Vaginal Vault Brachytherapy Applications

Evaluation of air cavities on dose distributions with air-filled apparatuses having different volumes using Gafchromic EBT3 films in brachytherapy

Evaluating the performance of TG-43 protocol in esophageal HDR brachytherapy viewpoint to trachea inhomogeneity

Contact Info

Product

Resources

About