The Efficacy of Collagen Membrane as a Biodegradable Wound Dressing Material for Surgical Defects of Oral Mucosa: A Prospective Study

Rastogi, Sanjay; Modi, Mancy; Sathian, Brijesh

doi:10.1016/j.joms.2008.12.020

Cited by 66 publications

(57 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was found as a very suitable alternative to the other graft material mentioned for the repair of defects in the mucous membrane created by surgical excision of fibrous bands in oral submucous fibrosis. Similar results were obtained in studies conducted by Sanjay Rastogi et al [7]. A collagen graft used as a biological dressing material is therefore advocated for use in the mouth to cover large areas devoid of mucous membrane.…”

Section: Resultssupporting

confidence: 81%

Role of Collagen Impregnated with Dexamethasone and Placentrix in Patients with Oral Submucous Fibrosis

Reddy

Srinath

Nandakumar

et al. 2011

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

Purpose To evaluate the versatility of the collagen membrane as both drug carrier and biologic dressing material to cover the raw wounds created after the surgical excision of fibrotic bands in oral submucous fibrosis. Materials and Methods The study comprises of ten patients. The patients of age group 20 to 50 years were selected. The collagen is reconstituted by injecting with dexamethasone and placentrix solution leaving a small overlap on to the remaining mucous membrane and the graft is sutured. Preoperative and post operative assessment was done regarding the improvement in mouth opening, decrease in burning sensation, change in colour of oral mucosa and clinically grading the extent of lesion. Results The results were found appreciable in seven patients while in the remaining three patients it showed relapse because of inadequate physiotherapy. All the ten patients were comfortable with intra oral collagen grafting. The collagen remained moist and supple intraorally, and remained in close contact with the underlying tissues, providing a strong mechanical barrier. The material was effective in attaining haemostasis, relieving pain and preventing extensive contracture. Conclusion In this study of short duration, the nature of collagen membrane was observed as both biological dressing material and drug carrier. It was found as a very suitable alternative to the other graft material mentioned for the repair of defects in the mucous membrane created by surgical excision of fibrous bands in oral submucous fibrosis.

show abstract

Section: Resultssupporting

confidence: 81%

Role of Collagen Impregnated with Dexamethasone and Placentrix in Patients with Oral Submucous Fibrosis

Reddy

Srinath

Nandakumar

et al. 2011

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

show abstract

“…Collagen consists of a repeating amino acid that constructs the connective tissue throughout the body, acting as the triple helix structure in tissues. An H atom of the side chain of glycine, links the NH peptide bond (amide II) and CH (amide III) of a glycine to a peptide carbonyl (C═O; amide I) group in an adjacent polypeptide and helps hold the three chains together and, therefore, can be involved in all 3 phases of the wound-healing cascade [15][16]. Collagen is the most abundant protein found in mammals; parts of an animal that can be the main sources of collagen for biomedical uses are skin or tendon, such as from rat-tail or bovine [17][18].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Chitosan/Collagen Blend Membranes for Wound Dressing: A Study on FTIR Spectroscopy and Mechanical Properties

Indrani

Lukitowati

Yulizar

2017

IOP Conf. Ser.: Mater. Sci. Eng.

View full text Add to dashboard Cite

Abstract. The effect of different gamma-ray irradiations on the functional groups and the mechanical properties of chitosan, collagen, and chitosan/collagen blend have been studied. Commercially available chitosan and extract of collagen from bovine tendon by acid dissolution method were employed. Chitosan, collagen and chitosan/collagen blend membranes were prepared using the solvent evaporation method. The dried membranes were subjected to gamma-ray irradiation using 0, 15, and 25 kGy. The membranes then characterized by Infrared spectroscopy and measured in tensile and elongation at break. The irradiated chitosan membranes displayed reduced intensity of -OH, -CH, -NH and -C-O-C groups, whereas, the collagen membranes revealed amide I, II and III groups. The irradiated chitosan/collagen (50/50%) blend membranes demonstrated the decreased intensities in the -OH and amide groups. The application of gamma-ray irradiation had produced chitosan/collagen blend membranes with a tensile strength and elongation at break between the chitosan and collagen membranes. It was further determined that the decrease in the mechanical properties of the membranes was likely to be due to some changes of the functional groups.

show abstract

“…It is an alternative to autologous grafts rather than being a replacement of other grafts used in orofacial region and can be viewed as a satisfactory additional armamentarium to oral surgeons. 37,39 Whatever the graft being used, the treatment should be coupled with cessation of betel quid/gutkha chewing and daily mouth opening exercises, and proper nutrition in order to manage both early and advanced stages of OSMF.…”

Section: Graph 5: Epithelialization Rate (Days)mentioning

confidence: 99%

Comparison of Efficacy of Buccal Fat Pad and Collagen Membrane in Surgical Management of Oral Submucous Fibrosis

Randhawa¹,

Randhawa²,

Tiwari³

et al. 2017

IJPCDR

View full text Add to dashboard Cite

Background and objectives: Oral submucous fibrosis (OSMF) is a chronic progressive premalignant condition, characterized by gradual trismus of mouth. The study was done to compare the efficacy of buccal fat pad (BFP) and collagen membrane as an interpositional material in surgical management of OSMF and also (1) to assess and compare the mouth opening achieved in both groups of patient; (2) the improvement in flexibility of buccal mucosa in both groups; (3) oral pain and burning sensation on intake of spicy food; (4) the rapidity in epithelialization of graft at the intraoral wound site.

show abstract

The Efficacy of Collagen Membrane as a Biodegradable Wound Dressing Material for Surgical Defects of Oral Mucosa: A Prospective Study

Cited by 66 publications

References 24 publications

Role of Collagen Impregnated with Dexamethasone and Placentrix in Patients with Oral Submucous Fibrosis

Role of Collagen Impregnated with Dexamethasone and Placentrix in Patients with Oral Submucous Fibrosis

Preparation of Chitosan/Collagen Blend Membranes for Wound Dressing: A Study on FTIR Spectroscopy and Mechanical Properties

Comparison of Efficacy of Buccal Fat Pad and Collagen Membrane in Surgical Management of Oral Submucous Fibrosis

Contact Info

Product

Resources

About